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Current Opinion in Orthopaedics - Current Table Of Contents
Journal of Orthopaedic Science
Iatrogenic calcinosis cutis following extravasation of calcium gluconate
Wed, 17 Dec 2008 08:22:29 -0000
Iatrogenic calcinosis cutis following extravasation of calcium gluconate Content Type Journal ArticleCategory Letter to the EditorDOI 10.1007/s00776-008-1282-yAuthors Anil Agarwal, CNBC, Geeta Colony Department of Paediatric Orthopaedics Delhi IndiaAnil Arora, UCMS and GTB Hospital, Shahdara Department of Orthopaedics Delhi IndiaMotoki Sonohata, Saga University Department of Orthopaedic Surgery, Faculty of Medicine 5-1-1 Nabeshima Saga 849-8501 Japan Journal Journal of Orthopaedic ScienceOnline ISSN 1436-2023Print ISSN 0949-2658 Journal Volume Volume 13 Journal Issue Volume 13, Number 6 / November, 2008
Unilateral stress fracture of the femoral shaft combined with contralateral insufficiency fracture of the femoral shaft after bilateral total knee arthroplasty
Wed, 17 Dec 2008 08:22:28 -0000
Unilateral stress fracture of the femoral shaft combined with contralateral insufficiency fracture of the femoral shaft after bilateral total knee arthroplasty Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00776-008-1262-2Authors Rui Niimi, Mie University Faculty of Medicine Department of Orthopaedic Surgery 2-174 Edobashi, Tsu Mie 514-8507 JapanMasahiro Hasegawa, Mie University Faculty of Medicine Department of Orthopaedic Surgery 2-174 Edobashi, Tsu Mie 514-8507 JapanAkihiro Sudo, Mie University Faculty of Medicine Department of Orthopaedic Surgery 2-174 Edobashi, Tsu Mie 514-8507 JapanAtsumasa Uchida, Mie University Faculty of Medicine Department of Orthopaedic Surgery 2-174 Edobashi, Tsu Mie 514-8507 Japan Journal Journal of Orthopaedic ScienceOnline ISSN 1436-2023Print ISSN 0949-2658 Journal Volume Volume 13 Journal Issue Volume 13, Number 6 / November, 2008
Rapidly destructive arthrosis of the hip joint after insufficiency fracture of the acetabulum
Wed, 17 Dec 2008 08:22:27 -0000
Rapidly destructive arthrosis of the hip joint after insufficiency fracture of the acetabulum Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00776-008-1261-3Authors Keisuke Watarai, Nishi-Tokyo Central General Hospital Department of Orthopaedic Surgery 2-4-19 Shibakubo-cho Nishi-Tokyo 188-0014 JapanHitoshi Taneda, Nishi-Tokyo Central General Hospital Department of Orthopaedic Surgery 2-4-19 Shibakubo-cho Nishi-Tokyo 188-0014 JapanMasanori Higano, Nishi-Tokyo Central General Hospital Department of Orthopaedic Surgery 2-4-19 Shibakubo-cho Nishi-Tokyo 188-0014 JapanYoichiro Hirasawa, Nishi-Tokyo Central General Hospital Department of Orthopaedic Surgery 2-4-19 Shibakubo-cho Nishi-Tokyo 188-0014 JapanHiromi Oda, Saitama Medical School Department of Orthopaedic Surgery Saitama Japan Journal Journal of Orthopaedic ScienceOnline ISSN 1436-2023Print ISSN 0949-2658 Journal Volume Volume 13 Journal Issue Volume 13, Number 6 / November, 2008
Electron microscopic study on bone formation and bioresorption after implantation of β-tricalcium phosphate in rabbit models
Wed, 17 Dec 2008 08:22:27 -0000
Abstract Background The role of bone formation and bioresorption in an early stage after implantation of β-tricalcium phosphate (β-TCP) was investigated using scanning and transmission electron microscopy (SEM, TEM). Methods The ceramic β-TCP cylinders were implanted into cavities drilled in the femoral condyles of eight NZW rabbits. Four of the rabbits were sacrificed at 2 weeks and four at 4 weeks after implantation, respectively. The femoral condyles were excised to prepare the specimens for SEM and TEM. Results SEM showed giant cells of more than 20 μm in diameter were observed on the surface of β-TCP at 2 weeks after implantation. TEM demonstrated that collagen fibrils secreted from the monocytic cells invaded β-TCP micropores at 2 weeks. Multinucleated giant cells (MNGCs) were in contact with the surface of β-TCP at 2 weeks. Some of them had a ruffled border (RB) at the cell-substrate interface, characteristic of osteoclasts. Conclusions These findings suggest that cell-mediated disintegration by osteoclasts played a role in the bioresorption of β-TCP at an early stage after implantation. In addition, the micropores of β-TCP ceramic may provide an environment for collagen formation, leading to the deposition of apatite crystals. Therefore, the micropores facilitate bone ingrowth as well as ceramic resorption. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00776-008-1271-1Authors Masaaki Chazono, The Jikei University School of Medicine Department of Orthopaedic Surgery 3-25-8 Nishi-shinbashi, Minato-ku Tokyo 105-8461 JapanTakaaki Tanaka, NHO Utsunomiya National Hospital Department of Orthopaedic Surgery Tochigi JapanSeiichiro Kitasato, The Jikei University School of Medicine Department of Orthopaedic Surgery 3-25-8 Nishi-shinbashi, Minato-ku Tokyo 105-8461 JapanTakahiro Kikuchi, NHO Utsunomiya National Hospital Department of Orthopaedic Surgery Tochigi JapanKeishi Marumo, The Jikei University School of Medicine Department of Orthopaedic Surgery 3-25-8 Nishi-shinbashi, Minato-ku Tokyo 105-8461 Japan Journal Journal of Orthopaedic ScienceOnline ISSN 1436-2023Print ISSN 0949-2658 Journal Volume Volume 13 Journal Issue Volume 13, Number 6 / November, 2008
Intermittent administration of human parathyroid hormone (1–34) increases new bone formation on the interface of hydroxyapatitecoated titanium rods implanted into ovariectomized rat femora
Wed, 17 Dec 2008 08:22:26 -0000
Abstract Background As hydroxyapatite (HA) has good osteoconductive properties, HA is used as coating material for the implants in cementless arthroplasty. However, its effect is not sufficient for osteoporotic bone. Parathyroid hormone (PTH) is known to have anabolic effects on bone formation. Intermittent administration of PTH increases both cancellous and cortical bone mass. The aim of this study was to confirm the effect of the fixation strength of HA-coated implants in the osteoporotic condition with a mechanical test and a bone histomorphometric method. Methods Female Sprague-Dawley rats were used for this study. Four weeks after ovariectomy (OVX) or sham surgery, HA-coated titanium rods were inserted into the distal femoral canal (Sham+HA group and OVX+HA group). PTH was administered immediately after the implantation of the HAcoated rods (OVX+HA+P group). We measured the shear strength at the bone-implant interface by a push-out test and the newly formed bone volume on the implant (BV.Im) by bone histomorphometry at 2 and 4 weeks after implantation. Results The bone-implant shear strength in the OVX+HA group was significantly lower than that in the Sham+HA group at 2 weeks after implantation of the rods. In the OVX+HA+P group, the strength was significantly higher than that in the other groups. Similarly, at 4 weeks, statistically significant differences were confirmed in the bone-implant shear strength among the Sham+HA group, the OVX+HA group, and the OVX+HA+P group. BV.Im in the OVX+HA group was significantly lower than that in the Sham+HA group at 2 weeks after implantation. BV.Im was significantly higher in the OVX+HA+P group than that in the OVX+HA group. However, there was no difference in BV.Im between the Sham+HA group and the OVX+HA+P group. At 4 weeks after implantation, BV.Im was significantly lower in the OVX+HA group than that in the other groups, but no difference was found between the Sham+HA group and the OVX+HA+P group. Conclusions Intermittent administration of PTH has an effect to increase new bone formation on the surface of HA-coated implants in the osteoporotic condition. This finding suggests that PTH administration is useful to improve the initial fixation of HA-coated implants even in osteoporotic patients. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00776-008-1275-xAuthors Yutaka Ohkawa, Niigata University Graduate School of Medical and Dental Sciences Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine 1-757 Asahimachi-dori, Chuo-ku Niigata 951-8510 JapanKunihiko Tokunaga, Niigata University Graduate School of Medical and Dental Sciences Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine 1-757 Asahimachi-dori, Chuo-ku Niigata 951-8510 JapanNaoto Endo, Niigata University Graduate School of Medical and Dental Sciences Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine 1-757 Asahimachi-dori, Chuo-ku Niigata 951-8510 Japan Journal Journal of Orthopaedic ScienceOnline ISSN 1436-2023Print ISSN 0949-2658 Journal Volume Volume 13 Journal Issue Volume 13, Number 6 / November, 2008
RGD peptide-induced cell death of chondrocytes and synovial cells
Wed, 17 Dec 2008 08:22:25 -0000
Abstract Background Small peptides including the Arg-Gly-Asp (RGD) motif have been used in studies on cell-extracellular matrix (ECM) attachment due to their ability to disturb integrin-mediated attachment on the cell surface. As another biological action of RGD peptides, several reports have shown that RGD peptides are incorporated into cytoplasm and induce apoptosis by direct activation of caspase-3. This study evaluated the effect of RGD peptides on chondrocytes and synovial cells and studied the involvement of caspases. Methods Chondrocytes and synovial cells were isolated and cultured from the knee joints of New Zealand White rabbits. Cells were incubated in serum-free medium with peptides (RGD, RGDS, GRGDSP, GRGDNP, RGES), and the survival rates were evaluated. The rate of apoptotic cells was measured by flow cytometry in cells treated with RGDS, GRGDSP, and RGES. Caspase-3, -8 and -9 activity was measured in cells treated with RGDS and GRGDSP. Osteochondral explants harvested from rabbits were also incubated with RGD peptides (RGDS, GRGDSP, and GRGDNP), and the survival rate of chondrocytes was evaluated. Results The survival rate of cultured chondrocytes was significantly decreased in the GRGDSP- and GRGDNP-treated groups. The survival rate of synovial cells was significantly decreased with four of the RGD peptides (RGD, RGDS, GRGDSP, and GRGDNP) at 5 mM, and in the RGDS- and GRGDSP-treated groups at 1 mM. Flow cytometric assay revealed increases of apoptotic chondrocytes with GRGDSP and increases of apoptotic synovial cells with RGDS and GRGDSP. Caspase-3 was activated in chondrocytes treated with GRGDSP and it was also activated in synovial cells treated with RGDS and GRGDSP. Caspases-8 and -9 were not activated in chondrocytes or in synovial cells. The survival rate of chondrocytes in explants decreased in the superficial layer with all three RGD peptides (RGDS, GRGDSP, and GRGDNP) and in the middle layer with GRGDSP. Conclusions RGD peptides induced apoptosis in cultured chondrocytes as well as in cells in cartilage explants and synovial cells, presumably through direct activation of caspase-3. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00776-008-1281-zAuthors Keisuke Matsuki, Chiba University Graduate School of Medicine Department of Orthopaedic Surgery 1-8-1 Inohana, Chuo-ku Chiba 260-8677 JapanTakahisa Sasho, Chiba University Graduate School of Medicine Department of Orthopaedic Surgery 1-8-1 Inohana, Chuo-ku Chiba 260-8677 JapanKoichi Nakagawa, Chiba University Graduate School of Medicine Department of Orthopaedic Surgery 1-8-1 Inohana, Chuo-ku Chiba 260-8677 JapanMasamichi Tahara, Chiba University Graduate School of Medicine Department of Orthopaedic Surgery 1-8-1 Inohana, Chuo-ku Chiba 260-8677 JapanKaori Sugioka, Chiba University Graduate School of Medicine Department of Orthopaedic Surgery 1-8-1 Inohana, Chuo-ku Chiba 260-8677 JapanNobuyasu Ochiai, Chiba University Graduate School of Medicine Department of Orthopaedic Surgery 1-8-1 Inohana, Chuo-ku Chiba 260-8677 JapanShuhei Ogino, Chiba University Graduate School of Medicine Department of Orthopaedic Surgery 1-8-1 Inohana, Chuo-ku Chiba 260-8677 JapanYuichi Wada, Teikyo University Chiba Medical Center Department of Orthopaedic Surgery Ichihara JapanHideshige Moriya, Chiba University Graduate School of Medicine Department of Orthopaedic Surgery 1-8-1 Inohana, Chuo-ku Chiba 260-8677 Japan Journal Journal of Orthopaedic ScienceOnline ISSN 1436-2023Print ISSN 0949-2658 Journal Volume Volume 13 Journal Issue Volume 13, Number 6 / November, 2008
PubMed: 1745-3674
C-reactive protein levels for early detection of postoperative infection after fracture surgery in 787 patients.
Jenny JY Related Articles C-reactive protein levels for early detection of postoperative infection after fracture surgery in 787 patients. Acta Orthop. 2008 Dec;79(6):874; author reply 874-5 Authors: Jenny JY PMID: 19097302 [PubMed - in process]
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Journal of Orthopaedic Science
Iatrogenic calcinosis cutis following extravasation of calcium gluconate
Wed, 17 Dec 2008 08:22:29 -0000
Iatrogenic calcinosis cutis following extravasation of calcium gluconate Content Type Journal ArticleCategory Letter to the EditorDOI 10.1007/s00776-008-1282-yAuthors Anil Agarwal, CNBC, Geeta Colony Department of Paediatric Orthopaedics Delhi IndiaAnil Arora, UCMS and GTB Hospital, Shahdara Department of Orthopaedics Delhi IndiaMotoki Sonohata, Saga University Department of Orthopaedic Surgery, Faculty of Medicine 5-1-1 Nabeshima Saga 849-8501 Japan Journal Journal of Orthopaedic ScienceOnline ISSN 1436-2023Print ISSN 0949-2658 Journal Volume Volume 13 Journal Issue Volume 13, Number 6 / November, 2008
Unilateral stress fracture of the femoral shaft combined with contralateral insufficiency fracture of the femoral shaft after bilateral total knee arthroplasty
Wed, 17 Dec 2008 08:22:28 -0000
Unilateral stress fracture of the femoral shaft combined with contralateral insufficiency fracture of the femoral shaft after bilateral total knee arthroplasty Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00776-008-1262-2Authors Rui Niimi, Mie University Faculty of Medicine Department of Orthopaedic Surgery 2-174 Edobashi, Tsu Mie 514-8507 JapanMasahiro Hasegawa, Mie University Faculty of Medicine Department of Orthopaedic Surgery 2-174 Edobashi, Tsu Mie 514-8507 JapanAkihiro Sudo, Mie University Faculty of Medicine Department of Orthopaedic Surgery 2-174 Edobashi, Tsu Mie 514-8507 JapanAtsumasa Uchida, Mie University Faculty of Medicine Department of Orthopaedic Surgery 2-174 Edobashi, Tsu Mie 514-8507 Japan Journal Journal of Orthopaedic ScienceOnline ISSN 1436-2023Print ISSN 0949-2658 Journal Volume Volume 13 Journal Issue Volume 13, Number 6 / November, 2008
Rapidly destructive arthrosis of the hip joint after insufficiency fracture of the acetabulum
Wed, 17 Dec 2008 08:22:27 -0000
Rapidly destructive arthrosis of the hip joint after insufficiency fracture of the acetabulum Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00776-008-1261-3Authors Keisuke Watarai, Nishi-Tokyo Central General Hospital Department of Orthopaedic Surgery 2-4-19 Shibakubo-cho Nishi-Tokyo 188-0014 JapanHitoshi Taneda, Nishi-Tokyo Central General Hospital Department of Orthopaedic Surgery 2-4-19 Shibakubo-cho Nishi-Tokyo 188-0014 JapanMasanori Higano, Nishi-Tokyo Central General Hospital Department of Orthopaedic Surgery 2-4-19 Shibakubo-cho Nishi-Tokyo 188-0014 JapanYoichiro Hirasawa, Nishi-Tokyo Central General Hospital Department of Orthopaedic Surgery 2-4-19 Shibakubo-cho Nishi-Tokyo 188-0014 JapanHiromi Oda, Saitama Medical School Department of Orthopaedic Surgery Saitama Japan Journal Journal of Orthopaedic ScienceOnline ISSN 1436-2023Print ISSN 0949-2658 Journal Volume Volume 13 Journal Issue Volume 13, Number 6 / November, 2008
Electron microscopic study on bone formation and bioresorption after implantation of β-tricalcium phosphate in rabbit models
Wed, 17 Dec 2008 08:22:27 -0000
Abstract Background The role of bone formation and bioresorption in an early stage after implantation of β-tricalcium phosphate (β-TCP) was investigated using scanning and transmission electron microscopy (SEM, TEM). Methods The ceramic β-TCP cylinders were implanted into cavities drilled in the femoral condyles of eight NZW rabbits. Four of the rabbits were sacrificed at 2 weeks and four at 4 weeks after implantation, respectively. The femoral condyles were excised to prepare the specimens for SEM and TEM. Results SEM showed giant cells of more than 20 μm in diameter were observed on the surface of β-TCP at 2 weeks after implantation. TEM demonstrated that collagen fibrils secreted from the monocytic cells invaded β-TCP micropores at 2 weeks. Multinucleated giant cells (MNGCs) were in contact with the surface of β-TCP at 2 weeks. Some of them had a ruffled border (RB) at the cell-substrate interface, characteristic of osteoclasts. Conclusions These findings suggest that cell-mediated disintegration by osteoclasts played a role in the bioresorption of β-TCP at an early stage after implantation. In addition, the micropores of β-TCP ceramic may provide an environment for collagen formation, leading to the deposition of apatite crystals. Therefore, the micropores facilitate bone ingrowth as well as ceramic resorption. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00776-008-1271-1Authors Masaaki Chazono, The Jikei University School of Medicine Department of Orthopaedic Surgery 3-25-8 Nishi-shinbashi, Minato-ku Tokyo 105-8461 JapanTakaaki Tanaka, NHO Utsunomiya National Hospital Department of Orthopaedic Surgery Tochigi JapanSeiichiro Kitasato, The Jikei University School of Medicine Department of Orthopaedic Surgery 3-25-8 Nishi-shinbashi, Minato-ku Tokyo 105-8461 JapanTakahiro Kikuchi, NHO Utsunomiya National Hospital Department of Orthopaedic Surgery Tochigi JapanKeishi Marumo, The Jikei University School of Medicine Department of Orthopaedic Surgery 3-25-8 Nishi-shinbashi, Minato-ku Tokyo 105-8461 Japan Journal Journal of Orthopaedic ScienceOnline ISSN 1436-2023Print ISSN 0949-2658 Journal Volume Volume 13 Journal Issue Volume 13, Number 6 / November, 2008
Intermittent administration of human parathyroid hormone (1–34) increases new bone formation on the interface of hydroxyapatitecoated titanium rods implanted into ovariectomized rat femora
Wed, 17 Dec 2008 08:22:26 -0000
Abstract Background As hydroxyapatite (HA) has good osteoconductive properties, HA is used as coating material for the implants in cementless arthroplasty. However, its effect is not sufficient for osteoporotic bone. Parathyroid hormone (PTH) is known to have anabolic effects on bone formation. Intermittent administration of PTH increases both cancellous and cortical bone mass. The aim of this study was to confirm the effect of the fixation strength of HA-coated implants in the osteoporotic condition with a mechanical test and a bone histomorphometric method. Methods Female Sprague-Dawley rats were used for this study. Four weeks after ovariectomy (OVX) or sham surgery, HA-coated titanium rods were inserted into the distal femoral canal (Sham+HA group and OVX+HA group). PTH was administered immediately after the implantation of the HAcoated rods (OVX+HA+P group). We measured the shear strength at the bone-implant interface by a push-out test and the newly formed bone volume on the implant (BV.Im) by bone histomorphometry at 2 and 4 weeks after implantation. Results The bone-implant shear strength in the OVX+HA group was significantly lower than that in the Sham+HA group at 2 weeks after implantation of the rods. In the OVX+HA+P group, the strength was significantly higher than that in the other groups. Similarly, at 4 weeks, statistically significant differences were confirmed in the bone-implant shear strength among the Sham+HA group, the OVX+HA group, and the OVX+HA+P group. BV.Im in the OVX+HA group was significantly lower than that in the Sham+HA group at 2 weeks after implantation. BV.Im was significantly higher in the OVX+HA+P group than that in the OVX+HA group. However, there was no difference in BV.Im between the Sham+HA group and the OVX+HA+P group. At 4 weeks after implantation, BV.Im was significantly lower in the OVX+HA group than that in the other groups, but no difference was found between the Sham+HA group and the OVX+HA+P group. Conclusions Intermittent administration of PTH has an effect to increase new bone formation on the surface of HA-coated implants in the osteoporotic condition. This finding suggests that PTH administration is useful to improve the initial fixation of HA-coated implants even in osteoporotic patients. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00776-008-1275-xAuthors Yutaka Ohkawa, Niigata University Graduate School of Medical and Dental Sciences Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine 1-757 Asahimachi-dori, Chuo-ku Niigata 951-8510 JapanKunihiko Tokunaga, Niigata University Graduate School of Medical and Dental Sciences Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine 1-757 Asahimachi-dori, Chuo-ku Niigata 951-8510 JapanNaoto Endo, Niigata University Graduate School of Medical and Dental Sciences Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine 1-757 Asahimachi-dori, Chuo-ku Niigata 951-8510 Japan Journal Journal of Orthopaedic ScienceOnline ISSN 1436-2023Print ISSN 0949-2658 Journal Volume Volume 13 Journal Issue Volume 13, Number 6 / November, 2008
RGD peptide-induced cell death of chondrocytes and synovial cells
Wed, 17 Dec 2008 08:22:25 -0000
Abstract Background Small peptides including the Arg-Gly-Asp (RGD) motif have been used in studies on cell-extracellular matrix (ECM) attachment due to their ability to disturb integrin-mediated attachment on the cell surface. As another biological action of RGD peptides, several reports have shown that RGD peptides are incorporated into cytoplasm and induce apoptosis by direct activation of caspase-3. This study evaluated the effect of RGD peptides on chondrocytes and synovial cells and studied the involvement of caspases. Methods Chondrocytes and synovial cells were isolated and cultured from the knee joints of New Zealand White rabbits. Cells were incubated in serum-free medium with peptides (RGD, RGDS, GRGDSP, GRGDNP, RGES), and the survival rates were evaluated. The rate of apoptotic cells was measured by flow cytometry in cells treated with RGDS, GRGDSP, and RGES. Caspase-3, -8 and -9 activity was measured in cells treated with RGDS and GRGDSP. Osteochondral explants harvested from rabbits were also incubated with RGD peptides (RGDS, GRGDSP, and GRGDNP), and the survival rate of chondrocytes was evaluated. Results The survival rate of cultured chondrocytes was significantly decreased in the GRGDSP- and GRGDNP-treated groups. The survival rate of synovial cells was significantly decreased with four of the RGD peptides (RGD, RGDS, GRGDSP, and GRGDNP) at 5 mM, and in the RGDS- and GRGDSP-treated groups at 1 mM. Flow cytometric assay revealed increases of apoptotic chondrocytes with GRGDSP and increases of apoptotic synovial cells with RGDS and GRGDSP. Caspase-3 was activated in chondrocytes treated with GRGDSP and it was also activated in synovial cells treated with RGDS and GRGDSP. Caspases-8 and -9 were not activated in chondrocytes or in synovial cells. The survival rate of chondrocytes in explants decreased in the superficial layer with all three RGD peptides (RGDS, GRGDSP, and GRGDNP) and in the middle layer with GRGDSP. Conclusions RGD peptides induced apoptosis in cultured chondrocytes as well as in cells in cartilage explants and synovial cells, presumably through direct activation of caspase-3. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00776-008-1281-zAuthors Keisuke Matsuki, Chiba University Graduate School of Medicine Department of Orthopaedic Surgery 1-8-1 Inohana, Chuo-ku Chiba 260-8677 JapanTakahisa Sasho, Chiba University Graduate School of Medicine Department of Orthopaedic Surgery 1-8-1 Inohana, Chuo-ku Chiba 260-8677 JapanKoichi Nakagawa, Chiba University Graduate School of Medicine Department of Orthopaedic Surgery 1-8-1 Inohana, Chuo-ku Chiba 260-8677 JapanMasamichi Tahara, Chiba University Graduate School of Medicine Department of Orthopaedic Surgery 1-8-1 Inohana, Chuo-ku Chiba 260-8677 JapanKaori Sugioka, Chiba University Graduate School of Medicine Department of Orthopaedic Surgery 1-8-1 Inohana, Chuo-ku Chiba 260-8677 JapanNobuyasu Ochiai, Chiba University Graduate School of Medicine Department of Orthopaedic Surgery 1-8-1 Inohana, Chuo-ku Chiba 260-8677 JapanShuhei Ogino, Chiba University Graduate School of Medicine Department of Orthopaedic Surgery 1-8-1 Inohana, Chuo-ku Chiba 260-8677 JapanYuichi Wada, Teikyo University Chiba Medical Center Department of Orthopaedic Surgery Ichihara JapanHideshige Moriya, Chiba University Graduate School of Medicine Department of Orthopaedic Surgery 1-8-1 Inohana, Chuo-ku Chiba 260-8677 Japan Journal Journal of Orthopaedic ScienceOnline ISSN 1436-2023Print ISSN 0949-2658 Journal Volume Volume 13 Journal Issue Volume 13, Number 6 / November, 2008
PubMed: 1745-3674
C-reactive protein levels for early detection of postoperative infection after fracture surgery in 787 patients.
Jenny JY Related Articles C-reactive protein levels for early detection of postoperative infection after fracture surgery in 787 patients. Acta Orthop. 2008 Dec;79(6):874; author reply 874-5 Authors: Jenny JY PMID: 19097302 [PubMed - in process]

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Academic Emergency Medicine: Web site for Academic Emergency Medicine.
Acta Orthopaedica Belgica: Presents original articles of basic research interest, as well as clinical studies in the field of orthopedics and related sub disciplines.
Acta Ortopedica Brasileira: Peer reviewed journal publishing articles on basic research and clinical studies in the field of orthopedics.
American Journal of Orthopedics: Peer review monthly orthopedics journal. Access to contents, abstracts, author, and subscription information.
Archives of Orthopaedic and Trauma Surgery: Archives of Orthopaedic and Trauma Surgery - Orthopedics. "Archives of Orthopaedic and Trauma Surgery" is a rich source of instruction and information for physicians in clinical practice and research in the extensive field...
Arthroscopy: journal of arthroscopic and related surgery: Explores trends and innovations in both diagnostic and operative arthroscopy.
Atlas of the Hand Clinics: Coverage of the latest procedures in hand surgery using detailed line drawings, photographs, and radiographs. Each issue focuses on a single topic.
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Clinical Orthopaedics and Related Research: Publishes invited, peer-reviewed original articles on general orthopedics and specialty topics covering the latest advances in current research and practice.
Clinics in Sports Medicine: Each issue focuses on a single topic in sports medicine and is presented under the direction of an experienced guest editor.
Current Opinion in Orthopaedics: Every other month journal of selected review topics. Information on subscription, current issue full text, author submissions, and contacts.
European Journal of Orthopaedic Surgery and Traumatology: Buy academic journals, books and online media at Springer. Choose from thousands of scientific, technology medical and business titles and view our range of services for authors, booksellers and librarians.
Hand Clinics: Each issue focuses on a single topic in hand surgery and is presented under the direction of an experienced guest editor.
Indian Journal of Orthopaedics: Website of the Indian Orthopaedic Association which represents Orthopaedic Surgeons and surgeons in training in India
Injury: Deals with all aspects of trauma, including fractures and soft-tissue injuries, and covers problems in the accident unit.
International Orthopaedics: International Orthopaedics - Orthopedics. International Orthopaedics, the Official Journal of the Société Internationale de Chirurgie Orthopédique et de Traumatologie (SICOT) http://www.sicot.org/, publishes original papers from all...
Iowa Orthopaedic Journal: Publishes articles relevant to orthopedic science, surgery and teaching
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Journal of Back and Musculoskeletal Rehabilitation: Provides clinicians with a current guide to the assessment, diagnosis, and management of back and musculoskeletal disorders
Journal of Bone and Joint Surgery: The Journal of Bone and Joint Surgery
Journal of Bone and Joint Surgery (British Volume): Web site for Journal of Bone and Joint Surgery - British Volume.
Journal of Bone and Mineral Research: Publishes papers on all areas of calcium regulation, skeletal physiology, and metabolic bone diseases.
Journal of Clinical Neuromuscular Disease: Articles of interest to physicians who treat patients with neuromuscular diseases. Contents, editorial board, author guide and subscription information.
Journal of Hand Surgery: Official bi-monthly journal of the American Society for Surgery of the Hand. Well respected American version.
Journal of Musculoskeletal and Neuronal Interactions: Details about JMNI, the current issue, past issues, submit an article and a search feature.
Journal of Orthopaedic Medicine.: Journal of Orthopaedic Medicine Home Page
Journal of Orthopaedic Research: Peer review journal published by the Orthpaedic Research Society.
Journal of Orthopaedic Surgery: Listed in MEDLINE database. Articles about orthopedic surgery and traumatology. Published by Asia Pacific Orthopaedic Association.
Journal of Orthopaedic Trauma: Official journal of the Orthopaedic Trauma Association and the International Society for Fracture Repair. Devoted to the diagnosis and management of hard and soft tissue trauma, including injuries to bone, muscle, ligament, and tendons.
Journal of Orthopaedics: Peer reviewed online journal with special focus on varying perspectives of orthopedic practice in tropical countries.
Journal of Pediatric Orthopaedics: Publication of the European Paediatric Orthopaedic Society and the Pediatric Orthopaedic Society of North America.
Journal of Pediatric Orthopaedics Part B: Quarterly journal with full-text content, online-only content, features and services, author submission materials and title-specific information.
Journal of Spinal Disorders: Features peer-reviewed articles on diagnosis, management, and clinically important laboratory investigations. Table of contents, author guidelines and subscription information.
Journal of the American Academy or Orthopaedic Surgeons: Web site for Journal of the American Academy of Orthopaedic Surgeons.
MedBioWorld: Links to Orthopaedics & Sports Medicine Journals
Orthopaedic Journal at Harvard Medical School: The Harvard Orthopaedic Journal is an annual publication of the Harvard Combined Orthopaedic Residency Program which includes Massachusetts General Hospital, The Children's Hospital, Beth Israel Deaconess Medical Center, and Brigham and Women's Hospital.
Orthopedic Clinics of North America: Each issue focuses on a single topic in orthopedics and is presented under the direction of an experienced guest editor.
Orthopedics: Blue journal. Monthly peer review journal of orthopedic management and research. Access to contents, abstracts, author, and subscription information.
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Techniques in Orthopaedics: Each issue deals with a single critical topic in the field, allowing for focused, in-depth coverage of important issues and clinical problems.
The Internet journal of orthopedic surgery: Provides information from the field of orthopedic surgery; contains original articles, reviews, case reports, streaming slide shows, streaming videos, letters to the editor, press releases, and meeting information.
The Journal of Knee Surgery: Provides a forum for practical, clinical information in such areas as arthroscopy, arthroplasty, magnetic resonance imaging, and reconstructive surgery.
The Spine Journal: The Spine Journal publishes original, peer-reviewed articles on research and treatment related to the spine and spine care. It is the official journal of the North American Spine Society with an international and multidisciplinary focus.
