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Permanent Orthopedics Job in Barstow California with Community Health Systems
Attractive High Desert, growing area - Barstow, CA - is located 90 miles East of LA. - midway between Los Angeles, CA and Las Vegas, NV. Currently this 56 bed acute care hospital - Seeking a solo opportunity?
Permanent Orthopedics Job in Petersburg Virginia with Community Health Systems
Seeking BC/BE Orthopedic Surgeon to join a 5-physician group in this lovely town located 15 miles south of Richmond, offering the best of smaller town living with the amenities of Richmond just a few
Permanent Orthopedics Job in Franklin Virginia with Community Health Systems
Solo private practice opportunity for aggressive Orthopedic Surgeon. Virginia Beach and North Carolina's Outer Banks are within one to two hours drive. Franklin is west of Suffolk (pop. 70,000), southeast

All Orthopedic Foot and Ankle Jobs

Permanent Orthopedic Foot and Ankle Job in Atlanta Georgia with Perimeter Outpatient Surgical Associates
Our North Atlanta Practice is looking to expand. We are seeking a fellowship trained orthopaedic physician (any specialty) to join our group and utilize our on site Ambulatory Surgical Center. Our
Permanent Orthopedic Foot and Ankle Job in Closed proximity to Dayton Beach and Orlando Florida with Enterprise Medical Services
Join a 7 person Orthopedic group in central Florida. The group is seeking a BC/BE ORS who is also fellowship trained in Foot and Ankle. Call will be 1:8. Will work out of two offices which are located
Permanent Orthopedic Foot and Ankle Job in Call for More Information Massachusetts with Medical Search International
Busy Medical Center with all sub specialties of Orthopedics is seeking a BC/BE Orthopedic Surgeon with Foot and Ankle training. Metropolitan area! Fellows are welcomed!! Great compensation including

Journal of Orthopaedic Trauma - Current Table Of Contents

Unstable Bicondylar Tibial Plateau Fractures: A Clinical Investigation.
Page: 673DOI: 10.1097/BOT.0b013e31818b1452Authors: Eggli, Stefan MD *; Hartel, Maximilian J MD *; Kohl, Sandro MD *; Haupt, Uli MD *; Exadaktylos, Aristomenis K MD +; Roder, Christoph MD ++
The Effect of Knee-Spanning External Fixation on Compartment Pressures in the Leg.
Page: 680DOI: 10.1097/BOT.0b013e31818afbdbAuthors: Egol, Kenneth A MD; Bazzi, Jamal MD; McLaurin, Toni M MD; Tejwani, Nirmal C MD
Irreducible Fracture-Dislocations of the Femoral Head Without Posterior Wall Acetabular Fractures.
Page: 686DOI: 10.1097/BOT.0b013e31818e2a86Authors: Mehta, Samir MD *; Routt, M L Chip Jr MD +

Archives of Orthopaedic and Trauma Surgery

The systemic angiogenic response during bone healing
Thu, 27 Nov 2008 09:20:57 -0000
Abstract Introduction  Angiogenesis is known to be a critical and closely regulated step during bone formation and fracture healing driven by a complex interaction of various cytokines. Delays in bone healing or even nonunion might therefore be associated with altered concentrations of specific angiogenic factors. These alterations might in turn be reflected by changes in serum concentrations. Method  To determine physiological time courses of angiogenic cytokines during fracture healing as well as possible changes associated with failed consolidation, we prospectively collected serum samples from patients who had sustained surgical treatment for a long bone fracture. Fifteen patients without fracture healing 4 months after surgery (nonunion group) were matched to a collective of 15 patients with successful healing (union group). Serum concentrations of angiogenin (ANG), angiopoietin 2 (Ang-2), basic fibroblast growth factor (bFGF), platelet derived growth factor AB (PDGF-AB), pleiotrophin (PTN) and vascular endothelial growth factor (VEGF) were measured using enzyme linked immunosorbent assays over a period of 24 weeks. Results  Compared to reference values of healthy uninjured controls serum concentrations of VEGF, bFGF and PDGF were increased in both groups. Peak concentrations of these cytokines were reached during early fracture healing. Serum concentrations of bFGF and PDGF-AB were significantly higher in the union group at 2 and 4 weeks after the injury when compared to the nonunion group. Serum concentrations of ANG and Ang-2 declined steadily from the first measurement in normal healing fractures, while no significant changes over time could be detected for serum concentrations of these factures in nonunion patients. PTN serum levels increased asymptotically over the entire investigation in timely fracture healing while no such increase could be detected during delayed healing. Conclusion  We conclude that fracture healing in human subjects is accompanied by distinct changes in systemic levels of specific angiogenic factors. Significant alterations of these physiologic changes in patients developing a fracture nonunion over time could be detected as early as 2 (bFGF) and 4 weeks (PDGF-AB) after initial trauma surgery. Content Type Journal ArticleCategory Basic ScienceDOI 10.1007/s00402-008-0777-5Authors Stefan Weiss, University of Heidelberg Department of Orthopaedics Heidelberg GermanyGerald Zimmermann, Berufsgenossenschaftliche Unfallklinik Ludwigshafen am Rhein GermanyThomas Pufe, University Hospital Aachen Department of Anatomy and Cellular Biology Aachen GermanyDeike Varoga, University Hospital of Schleswig-Holstein Department of Orthopaedic Surgery Kiel GermanyPhilipp Henle, University of Heidelberg Department of Orthopaedics Heidelberg Germany Journal Archives of Orthopaedic and Trauma SurgeryOnline ISSN 1434-3916Print ISSN 0936-8051
Functional outcomes of arthroscopic posterior cruciate ligament reconstruction: comparison of anteromedial and anterolateral trans-tibia approach
Wed, 26 Nov 2008 19:58:40 -0000
Abstract Introduction  The hypothesis of this study is that anterolateral (A-L) trans-tibia approach is better than anteromedial (A-M) technique in posterior cruciate ligament (PCL) reconstruction. The purpose of this prospective clinical study was to compare the functional outcomes of A-M and A-L trans-tibia approach in arthroscopic PCL reconstruction. Materials and methods  Between 1999 and 2003, 55 patients (55 knees) with an average age of 30 ± 11 years (range 16–60 years) underwent arthroscopic single-bundle reconstruction for symptomatic isolated PCL tear. Patients were randomly divided into two groups with 28 patients (28 knees) undergoing A-M trans-tibia approach on odd-numbered days, and 27 patients (27 knees) with A-L trans-tibia approach on even-numbered days. Hamstring auto grafts were used in all cases. All patients received the same rehabilitation program postoperatively. The evaluation parameters included clinical assessment, functional outcome, ligament laxity and radiographic changes of the affected knee. Results  Significant improvements in pain and function of the knee were observed at an average follow-up of 48 ± 15.9 months for A-M and 45.0 ± 13.7 months for A-L approach. However, the difference between the two techniques was statistically not significant. In IKDC for symptom-activity level, normal or nearly normal knees were noted in 68% of A-M and 67% of A-L approach, respectively, but no difference was noted between the two groups. In ligament laxity, approximately two-thirds of the knees showed normal posterior laxity with no difference between the two groups. Radiographs of the knee showed no discernible difference in the overall alignment and degenerative changes as well as the sizes of bone tunnel between the two groups. Conclusion  A-M and A-L trans-tibia arthroscopic PCL reconstructions produced comparable clinical results in short-term follow-up. Contrary to our initial hypothesis, the theoretical disadvantages of A-M technique including graft failure were not observed during the follow-up period. Long-term results are needed to confirm the adverse effects of A-M trans-tibia approach in PCL reconstruction. Content Type Journal ArticleCategory Arthroscopy and Sports MedicineDOI 10.1007/s00402-008-0787-3Authors To Wong, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine Department of Orthopedics and Sports Medicine 123 Ta-Pei Road, Niao-Sung Hsiang Kaohsiung 833 TaiwanChing-Jen Wang, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine Department of Orthopedics and Sports Medicine 123 Ta-Pei Road, Niao-Sung Hsiang Kaohsiung 833 TaiwanLin-Hsiu Weng, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine Department of Orthopedics and Sports Medicine 123 Ta-Pei Road, Niao-Sung Hsiang Kaohsiung 833 TaiwanShan-Ling Hsu, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine Department of Orthopedics and Sports Medicine 123 Ta-Pei Road, Niao-Sung Hsiang Kaohsiung 833 TaiwanWen-Yi Chou, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine Department of Orthopedics and Sports Medicine 123 Ta-Pei Road, Niao-Sung Hsiang Kaohsiung 833 TaiwanJune-Ming Chen, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine Department of Orthopedics and Sports Medicine 123 Ta-Pei Road, Niao-Sung Hsiang Kaohsiung 833 TaiwanYi-Sheng Chan, Chang Gung Memorial Hospital-Lin Kou Medical Center, Chang Gung University College of Medicine Department of Orthopedics and Sports Medicine Kaohsiung Taiwan Journal Archives of Orthopaedic and Trauma SurgeryOnline ISSN 1434-3916Print ISSN 0936-8051
Treatment of osteomyelitis by liposomal gentamicin-impregnated calcium sulfate
Wed, 26 Nov 2008 19:58:40 -0000
Abstract Objectives  Traditional therapy of staphylococcal osteomyelitis is ineffective in producing complete sterilization of infected bones due to the formation of the Staphylococcus aureus biofilms. The aim of this study was to develop a new drug-delivery system of antibiotics for treatment of chronic experimental osteomyelitis. Methods  In the current work, cationic liposomal gentamicin was prepared and impregnated in calcium sulfate (CS), and tested for anti-biofilm activities in vitro and in vivo. Results and conclusions  The combination of liposomal gentamicin and CS showed initial burst-release of active liposomal gentamicin and had continuous-release (12 days). Liposomal gentamicin released from CS had the same anti-biofilm activity with the liposomal gentamicin prepared freshly. Meanwhile, both agents were more effective relative to free gentamicin at low drug concentration. Therapeutic trials with antibiotics given intravenously revealed that free gentamicin for 14 days was ineffective in sterilizing bone. Treatment with liposomal gentamicin for 14 days resulted in recovery of 33.3% of treated animals, which was the lower slightly than the result treated with implantation of gentamicin-impregnated CS (66.7%). Complete sterilization of bone tissues on cultures (100% cure) was obtained only in the group of liposomal gentamicin-impregnated CS treated for 14 days. The new drug-delivery system was effective in preventing biofilm infection in a contaminated defect, and it could also be used clinically for bacterial infections in the conditions like plaque formation or in arresting biofilm formation in the implanted devices or dead bone of osteomyelitis. Content Type Journal ArticleCategory Orthopaedic SurgeryDOI 10.1007/s00402-008-0782-8Authors Tang Hui, Kunming General Hospital of Chengdu Military Command Orthopedic Center Kunming ChinaXu Yongqing, Kunming General Hospital of Chengdu Military Command Orthopedic Center Kunming ChinaZheng Tiane, Kunming General Hospital of Chengdu Military Command Department of Ophthalmology Kunming ChinaLi Gang, Kunming General Hospital of Chengdu Military Command Orthopedic Center Kunming ChinaYou Yonggang, Kunming General Hospital of Chengdu Military Command Orthopedic Center Kunming ChinaJiang Muyao, Kunming General Hospital of Chengdu Military Command Orthopedic Center Kunming ChinaLi Jun, Kunming General Hospital of Chengdu Military Command Orthopedic Center Kunming ChinaDing Jing, Kunming General Hospital of Chengdu Military Command Orthopedic Center Kunming China Journal Archives of Orthopaedic and Trauma SurgeryOnline ISSN 1434-3916Print ISSN 0936-8051
Short-term results of hip revisions with a curved cementless modular stem in association with the surgical approach
Wed, 26 Nov 2008 19:58:40 -0000
Short-term results of hip revisions with a curved cementless modular stem in association with the surgical approach Content Type Journal ArticleCategory ErratumDOI 10.1007/s00402-008-0785-5Authors Bernd Fink, Orthopaedic Clinic Markgröningen gGmbH Clinic of Joint Replacement, General and Rheumatic Orthopaedics Kurt-Lindemann-Weg 10 71706 Markgröningen GermanyAlexandra Grossmann, Orthopaedic Clinic Markgröningen gGmbH Clinic of Joint Replacement, General and Rheumatic Orthopaedics Kurt-Lindemann-Weg 10 71706 Markgröningen GermanySvenja Schubring, Orthopaedic Department of Rheumaklinik Bad Bramstedt Oskar-Alexander-Str. 26 24576 Bad Bramstedt GermanyMartin S. Schulz, Orthopaedic Clinic Markgröningen gGmbH Clinic of Joint Replacement, General and Rheumatic Orthopaedics Kurt-Lindemann-Weg 10 71706 Markgröningen GermanyMartin Fuerst, Orthopaedic Department of Rheumaklinik Bad Bramstedt Oskar-Alexander-Str. 26 24576 Bad Bramstedt Germany Journal Archives of Orthopaedic and Trauma SurgeryOnline ISSN 1434-3916Print ISSN 0936-8051
Graft remodeling during growth following anterior cruciate ligament reconstruction in skeletally immature sheep
Fri, 21 Nov 2008 06:55:34 -0000
Abstract Introduction  Ruptures of the anterior cruciate ligament are being diagnosed with increasing frequency in skeletally immature individuals. It was our aim to investigate the graft remodelling process following an autologous, transphyseal reconstruction of the anterior cruciate ligament (ACL) in skeletally immature sheep. We hypothesized that the ligamentisation process in immature sheep is quicker and more complete when compared to adult sheep. Materials and methods  Skeletally immature sheep with an age of 4 months underwent a fully transphyseal ACL reconstruction using an autologous tendon. The animals were subsequently sacrificed at 3, 6, 12 and 24 weeks following surgery. Each group was characterised histomorphometrically, by immunostaining (VEGF, SMA), by transmission electron microscopy (TEM) and biomechanically (UFS Roboter). Results  The histomorphometric analysis and presence of VEGF and SMA positive cells demonstrated a rapid return to a ligament like structure. The biomechanical analysis revealed an anteroposterior translation that was still increased even 6 months following surgery. Conclusion  As in adult sheep models, the remodeling of a soft tissue graft used for ACL reconstruction results in a biomechanically inferior substitute. However, the immature tissue seems to remodel faster and more complete when compared to adults. Content Type Journal ArticleCategory Arthroscopy and Sports MedicineDOI 10.1007/s00402-008-0784-6Authors Rupert Meller, Hannover Medical School (MHH) Trauma Department Carl-Neuberg-Strasse 1 30625 Hannover GermanyG. Brandes, Hannover Medical School Institute of Cell Biology, Center of Anatomy Hannover GermanyC. Drögemüller, University of Veterinary Medicine Hannover Institutes for Animal Breeding and Genetics Hannover GermanyF. Fritz, Hannover Medical School (MHH) Trauma Department Carl-Neuberg-Strasse 1 30625 Hannover GermanyF. Schiborra, Hannover Medical School (MHH) Trauma Department Carl-Neuberg-Strasse 1 30625 Hannover GermanyM. Fehr, University of Veterinary Medicine Hannover Small Animal Clinic Hannover GermanyS. Hankemeier, Hannover Medical School (MHH) Trauma Department Carl-Neuberg-Strasse 1 30625 Hannover GermanyC. Krettek, Hannover Medical School (MHH) Trauma Department Carl-Neuberg-Strasse 1 30625 Hannover GermanyC. Hurschler, Hannover Medical School Orthopaedic Department Hannover Germany Journal Archives of Orthopaedic and Trauma SurgeryOnline ISSN 1434-3916Print ISSN 0936-8051
Remodeling potentials of biphasic calcium phosphate granules in open wedge high tibial osteotomy
Tue, 18 Nov 2008 08:00:36 -0000
Abstract Introduction  Biphasic calcium phosphate (BCP) has proved to be an effective bone substitute, but it’s effectiveness and remodeling potential in open wedge high tibial osteotomy (OWHTO) has not been analyzed yet. This study sought to evaluate the bone healing and remodeling potentials of BCP granules using a radiographic rating system in biplanar OWHTO. Materials and methods  Fifteen patients (15 knees) underwent biplanar OWHTO. Bone gaps were filled with BCP granules. For radiographic evaluation, remodeling was divided into four phases. Phase 1 was accepted as rounded osteotomy sites, with clear distinction between BCP and bone, phase 2 was accepted as whitened osteotomy sites, with distinction between BCP and bone still visible, phase 3 was accepted as distinction between BCP and bone not visible and cloudy bone formation and phase 4 was accepted as full reformation of BCP granules (4A-BCP visible, 4B-disappearence of BCP) with no sign of osteotomy. Bone union was confirmed with clinical (full weight bearing without pain) and radiographic evaluation (cortical bridging callus on radiographs and phase 3 or greater remodeling). The time to full remodeling and the starting point of the consolidation on anteroposterior radiographs were noted. Complications were also noted at each clinical follow-up. Results  Mean follow-up was 27.2 months. The mean age was 55.8 years. At clinical follow-up, there were no wound healing problems, no loss of corrections, no infections, and no complications. All osteotomies successfully healed. According to the radiologic classification system, at the 6th week, 73.3% (11/15) of patients were in phase 1 and the remaining 26.7% (4/15) were in phase 2. At 12-month follow-up, 46.7 (7/15) of the patients were still in phase 3. After 2 years, all radiographs showed to be in phase 4A. Radiographic union was noted to progress from lateral to medial and finally central. Conclusions  BCP can be successfully used as a bone substitute. The radiographic remodeling and consolidation process of BCP was found to be different from that of beta-tricalcium phosphate. In our patients with more than 2 years of follow-up, BCP granules did not completely remodel. As a result, this clinical study demonstrated that calcium phosphate granules containing hydroxyapatite had a long period of “creeping substitution” that lasts longer than 2 years. Content Type Journal ArticleCategory Orthopaedic SurgeryDOI 10.1007/s00402-008-0781-9Authors Metin Ozalay, Baskent University Hospital Department of Orthopaedics and Traumatology Fevzi Cakmak Cad. 10. Sok. No: 45, Bahcelievler 06100 Ankara TurkeyOrcun Sahin, Baskent University Hospital Department of Orthopaedics and Traumatology Fevzi Cakmak Cad. 10. Sok. No: 45, Bahcelievler 06100 Ankara TurkeySercan Akpinar, Baskent University Hospital Department of Orthopaedics and Traumatology Fevzi Cakmak Cad. 10. Sok. No: 45, Bahcelievler 06100 Ankara TurkeyGurkan Ozkoc, Baskent University Hospital Department of Orthopaedics and Traumatology Fevzi Cakmak Cad. 10. Sok. No: 45, Bahcelievler 06100 Ankara TurkeyMurat Cinar, Baskent University Hospital Department of Orthopaedics and Traumatology Fevzi Cakmak Cad. 10. Sok. No: 45, Bahcelievler 06100 Ankara TurkeyNecip Cesur, Baskent University Hospital Department of Orthopaedics and Traumatology Fevzi Cakmak Cad. 10. Sok. No: 45, Bahcelievler 06100 Ankara Turkey Journal Archives of Orthopaedic and Trauma SurgeryOnline ISSN 1434-3916Print ISSN 0936-8051

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