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Journal of Clinical Gastroenterology - Current Table Of Contents
Biography of Dr. Khursheed N. Jeejeebhoy.
Page: 1DOI: 10.1097/MCG.0b013e31818a8482Authors: Lewis, Myron MD, FACP, MACG
PubMed: 1542-3565
A Retrospective Single-Center Review of Primary Sclerosing Cholangitis in Children.
Miloh T, Arnon R, Shneider B, Suchy F, Kerkar N Related Articles A Retrospective Single-Center Review of Primary Sclerosing Cholangitis in Children. Clin Gastroenterol Hepatol. 2008 Oct 30; Authors: Miloh T, Arnon R, Shneider B, Suchy F, Kerkar N BACKGROUND & AIMS: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by inflammation and progressive bile duct fibrosis. There are limited data on pediatric PSC. METHODS: We performed a retrospective chart review of 47 pediatric patients with PSC. RESULTS: The mean age at diagnosis was 11 +/- 4.9 years. Symptoms occurred before presentation in 81% of patients; inflammatory bowel disease was found in 59% and autoimmune hepatitis (overlap syndrome) in 25% of patients. Magnetic resonance cholangiography revealed both extrahepatic and intrahepatic, isolated intrahepatic, isolated extrahepatic, and no biliary involvement (small-duct PSC) in 40%, 14%, 10%, and 36%, respectively. Advanced fibrosis (stage > II) was present in 65%. Colonoscopy revealed pancolitis, rectal sparing, and normal findings in 24%, 24%, and 18%, respectively. All patients were treated with ursodeoxycholic acid (UDCA); 9 with overlap syndrome also received immunosuppressants. Fifteen patients without overlap syndrome had positive autoimmune markers and responded to UDCA monotherapy. Liver transplantation was performed in 9 patients (3 with overlap syndrome and 2 with small-duct PSC) at a median time of 7 years after diagnosis. The 10-year posttransplant survival rate was 89%. CONCLUSIONS: In one of the largest single-center studies of children with PSC, we found that most children with PSC had inflammatory bowel disease or autoimmune overlap and advanced fibrosis at diagnosis. Levels of alanine aminotransferase and gamma-glutamyl transferase were highest in patients with overlap syndrome and lowest in those with small-duct PSC. Levels of serum liver enzymes normalized after therapy with UDCA, including patients with positive autoimmune markers without histologic features of autoimmune hepatitis. PMID: 19121649 [PubMed - as supplied by publisher]
Current Opinion in Gastroenterology - Current Table Of Contents
Editorial introductions.
Page: viiDOI: 10.1097/MOG.0b013e32831f1eef
European Journal of Gastroenterology & Hepatology - Current Table Of Contents
Ulcerative colitis: current medical therapy and strategies for improving medication adherence.
Page: 1DOI: 10.1097/MEG.0b013e32830bfb88Authors: Zhang, Zunwu; Kennedy, Hugh
Evidence-Based Gastroenterology - Current Table Of Contents
Letter From the Editor.
Page: 59DOI: 10.1097/EBG.0b013e31818e1d57Authors: Eisen, Glenn MD, MPH
Nature Clinical Practice Gastroenterology & Hepatology
Sitting on the fence
Stephen B Hanauer Sitting on the fence Nature Clinical Practice Gastroenterology & Hepatology 5, 655 (2008). doi:10.1038/ncpgasthep1302 Author: Stephen B Hanauer
Inflammatory Bowel Diseases
Human neutrophil peptides 1-3 are useful biomarkers in patients with active ulcerative colitis
Shuji Kanmura, Hirofumi Uto, Masatsugu Numata, Shinichi Hashimoto, Akihiro Moriuchi, Hiroshi Fujita, Makoto Oketani, Akio Ido, Mayumi Kodama, Hidehisa Ohi, Hirohito Tsubouchi Tue, 23 Dec 2008 09:13:00 -0000
Background: A specific useful biomarker for diagnosing ulcerative colitis (UC) has not yet been described. This study employed proteomics to identify serum protein biomarkers for UC.Methods: Ninety-four blood samples were isolated from patients and controls (including 48 UC, 22 Crohn's disease [CD], 5 colorectal cancer, and 6 infectious colitis patients and 13 healthy subjects). Serum samples were analyzed using the SELDI-TOF/MS ProteinChip system. After applying the samples to ProteinChip arrays, we assessed differences in the proteomes using Ciphergen ProteinChip software and identified candidate proteins, which were then characterized in immunoassays.Results: Preliminary analysis using the ProteinChip system revealed significant peak-intensity differences for 27 serum proteins between 11 patients with UC and 7 healthy subjects. Among these proteins, 3 proteins (with mass/charge ratios of approximately 3400) were identified as human neutrophil peptides 1-3 (HNP 1-3). The presence of HNP 1-3 in the patient sera was confirmed using immunoassays. Enzyme-linked immunosorbent assays demonstrated that the mean plasma concentration of HNP 1-3 was significantly higher in patients with active UC (n = 28) than in patients whose UC was in remission (n = 20) or patients with CD (n = 22), infectious colitis, or healthy subjects, and tended to be higher than in patients with colon cancer. In addition, the plasma concentration of HNP 1-3 in patients that responded to corticosteroids-based therapy decreased after treatment, whereas it was not changed in nonresponders.Conclusions: HNP 1-3 is a novel biomarker that may be useful for diagnosing patients with active UC and predicting treatment outcomes.(Inflamm Bowel Dis 2008)
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Biography of Dr. Khursheed N. Jeejeebhoy.
Page: 1DOI: 10.1097/MCG.0b013e31818a8482Authors: Lewis, Myron MD, FACP, MACG
PubMed: 1542-3565
A Retrospective Single-Center Review of Primary Sclerosing Cholangitis in Children.
Miloh T, Arnon R, Shneider B, Suchy F, Kerkar N Related Articles A Retrospective Single-Center Review of Primary Sclerosing Cholangitis in Children. Clin Gastroenterol Hepatol. 2008 Oct 30; Authors: Miloh T, Arnon R, Shneider B, Suchy F, Kerkar N BACKGROUND & AIMS: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by inflammation and progressive bile duct fibrosis. There are limited data on pediatric PSC. METHODS: We performed a retrospective chart review of 47 pediatric patients with PSC. RESULTS: The mean age at diagnosis was 11 +/- 4.9 years. Symptoms occurred before presentation in 81% of patients; inflammatory bowel disease was found in 59% and autoimmune hepatitis (overlap syndrome) in 25% of patients. Magnetic resonance cholangiography revealed both extrahepatic and intrahepatic, isolated intrahepatic, isolated extrahepatic, and no biliary involvement (small-duct PSC) in 40%, 14%, 10%, and 36%, respectively. Advanced fibrosis (stage > II) was present in 65%. Colonoscopy revealed pancolitis, rectal sparing, and normal findings in 24%, 24%, and 18%, respectively. All patients were treated with ursodeoxycholic acid (UDCA); 9 with overlap syndrome also received immunosuppressants. Fifteen patients without overlap syndrome had positive autoimmune markers and responded to UDCA monotherapy. Liver transplantation was performed in 9 patients (3 with overlap syndrome and 2 with small-duct PSC) at a median time of 7 years after diagnosis. The 10-year posttransplant survival rate was 89%. CONCLUSIONS: In one of the largest single-center studies of children with PSC, we found that most children with PSC had inflammatory bowel disease or autoimmune overlap and advanced fibrosis at diagnosis. Levels of alanine aminotransferase and gamma-glutamyl transferase were highest in patients with overlap syndrome and lowest in those with small-duct PSC. Levels of serum liver enzymes normalized after therapy with UDCA, including patients with positive autoimmune markers without histologic features of autoimmune hepatitis. PMID: 19121649 [PubMed - as supplied by publisher]
Current Opinion in Gastroenterology - Current Table Of Contents
Editorial introductions.
Page: viiDOI: 10.1097/MOG.0b013e32831f1eef
European Journal of Gastroenterology & Hepatology - Current Table Of Contents
Ulcerative colitis: current medical therapy and strategies for improving medication adherence.
Page: 1DOI: 10.1097/MEG.0b013e32830bfb88Authors: Zhang, Zunwu; Kennedy, Hugh
Evidence-Based Gastroenterology - Current Table Of Contents
Letter From the Editor.
Page: 59DOI: 10.1097/EBG.0b013e31818e1d57Authors: Eisen, Glenn MD, MPH
Nature Clinical Practice Gastroenterology & Hepatology
Sitting on the fence
Stephen B Hanauer Sitting on the fence Nature Clinical Practice Gastroenterology & Hepatology 5, 655 (2008). doi:10.1038/ncpgasthep1302 Author: Stephen B Hanauer
Inflammatory Bowel Diseases
Human neutrophil peptides 1-3 are useful biomarkers in patients with active ulcerative colitis
Shuji Kanmura, Hirofumi Uto, Masatsugu Numata, Shinichi Hashimoto, Akihiro Moriuchi, Hiroshi Fujita, Makoto Oketani, Akio Ido, Mayumi Kodama, Hidehisa Ohi, Hirohito Tsubouchi Tue, 23 Dec 2008 09:13:00 -0000
Background: A specific useful biomarker for diagnosing ulcerative colitis (UC) has not yet been described. This study employed proteomics to identify serum protein biomarkers for UC.Methods: Ninety-four blood samples were isolated from patients and controls (including 48 UC, 22 Crohn's disease [CD], 5 colorectal cancer, and 6 infectious colitis patients and 13 healthy subjects). Serum samples were analyzed using the SELDI-TOF/MS ProteinChip system. After applying the samples to ProteinChip arrays, we assessed differences in the proteomes using Ciphergen ProteinChip software and identified candidate proteins, which were then characterized in immunoassays.Results: Preliminary analysis using the ProteinChip system revealed significant peak-intensity differences for 27 serum proteins between 11 patients with UC and 7 healthy subjects. Among these proteins, 3 proteins (with mass/charge ratios of approximately 3400) were identified as human neutrophil peptides 1-3 (HNP 1-3). The presence of HNP 1-3 in the patient sera was confirmed using immunoassays. Enzyme-linked immunosorbent assays demonstrated that the mean plasma concentration of HNP 1-3 was significantly higher in patients with active UC (n = 28) than in patients whose UC was in remission (n = 20) or patients with CD (n = 22), infectious colitis, or healthy subjects, and tended to be higher than in patients with colon cancer. In addition, the plasma concentration of HNP 1-3 in patients that responded to corticosteroids-based therapy decreased after treatment, whereas it was not changed in nonresponders.Conclusions: HNP 1-3 is a novel biomarker that may be useful for diagnosing patients with active UC and predicting treatment outcomes.(Inflamm Bowel Dis 2008)
Sites:
Nutrition Magazine: Domain name renewal and affordable web hosting packages from Network SolutionsResearch Clinical Gastroenterology: Review of current clinical practice and thinking within the specialty of gastroenterology
Wilkins - Inflammatory Bowel Disease: Devoted exclusively to Inflammatory Bowel Diseases and covers topics of interest to professionals treating patients or conducting research on inflammatory bowel diseases.
Wilkins - Pancreas: Official Journal of the American Pancreatic Association and the Japan Pancreas Society.
Abdominal Imaging: Abdominal Imaging - New & Forthcoming Titles. Abdominal Imaging is designed for prompt publication of original articles dealing with clinical radiology of abdominal disorders, including the alimentary tract and the genitourinary...
Abdominal Surgery: The official journal of the American Society of Abdominal Surgeons with a focus on surgical management of abdominal diseases and new deveolopments in surgery.
Acta Endoscopica: Journal of original articles concerning endoscopy.
Acta Gastroenterologica: Official Belgian journal publishing articles, review and case reports in the field of gastroenterology, hepatology and endoscopy.
AJP - Gastrointestinal and Liver Physiology: Web site for AJP - Gastrointestinal and Liver Physiology.
Alimentary Pharmacology and Therapeutics Aims: Alimentary Pharmacology and Therapeutics: journal information, contents lists and abstracts on the Blackwell Publishing website.
Archives of Gastroenterohepatology: Quarterly journal devoted to clinical and basic studies of the digestive tract published by the Serbian Medical Association - Section for Gastroenterology.
Audio-Digest Foundation: Gastroenterology: Providing physicians and healthcare professionals with Category 1 continuing medical education (CME) and (CE) audio
Clinical Nutrition: The official journal of the European Society of Parenteral Enteral Nutrition and provides scientific information on nutritional and metabolic care and the relationship between nutrition and disease both in the setting of basic science and clinical practice.
Clinical Perspectives in Gastroenterology: Features articles, columns and stories on managed care, patient care, and digestive disease prevention, diagnosis and management.
Clinics in Colon and Rectal Surgery: 15310043| Product Information page
Clinics in Liver Disease: Provides current, practical information on the diagnosis and treatment of conditions affecting the liver and biliary tract. Each issue focuses on a single topic.
Current Opinion in Clinical Nutrition and Metabolic Care: Focuses on nutritional and metabolic aspects of patient care.
Current Opinion in Gastroenterology: Review and update articles on gastroenterology with a annotated bibliography of papers published in the preceding year relating to the topics.
Digestive Diseases: Covers both clinical and basic science topics in gastrointestinal function and disorders.
Digestive Endoscopy: Digestive Endoscopy: journal information, contents lists and abstracts on the Blackwell Publishing website.
Diseases of the Esophagus: Diseases of the Esophagus: journal information, contents lists and abstracts on the Blackwell Publishing website.
Dysphagia: Dysphagia - Otorhinolaryngology. Dysphagia is a multidisciplinary journal devoted to swallowing and its disorders. The journal's purpose is to provide an international source of information to physicians and other health profes...
Endoscopy: Focus on international developments in gastrointestinal endoscopy.
European Journal of Gastroenterology and Hepatology: Official Journal of the European Association for Gastroenterology and Endoscopy with original research, reviews and commentaries.
Evidence-Based Gastroenterology: Publication of research and reports on new procedures and advances in gastroenterology. Emphasis is placed on providing information based on the best current evidence.
Gastric Cancer: Gastric Cancer - Oncology & Hematology. Gastric Cancer, a joint official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, publishes significant studies related to stomach neopl...
Gastroenterology: Focused on new developments in all aspects of gastroenterology. Includes both clinical and bench research. This is the official journal of the American Gastroenterological Association.
Gastroenterology Clinics of North America: Each issue focuses on a single topic in gastroenterology and is presented under the direction of an experienced guest editor.
Gastroenterology Coding Information - The Coding Institute: medical diagnosis coding and compliance publications optimize medical office reimbursement. the coding institute offers medical coding alert series, medical teleconferences, medical seminars and medical books.
Gastrointestinal Endoscopy: Publishes original, peer-reviewed articles on endoscopic procedures used in the study, diagnosis, and treatment of digestive diseases. This is the official Journal of the American Society for Gastrointestinal Endoscopy.
Gastrointestinal Endoscopy Clinics of North America: Each issue focuses on a single topic in gastrointestinal endoscopy and is presented under the direction of an experienced guest editor.
Gut: Gut, a peer review journal for health professionals and researchers in all areas of neurology
Hépato-Gastro: French journal focused on digestive pathology. It is both teaching tool as well as a reference journal.
Helicobacter: Covers the entire field of Helicobacter research, and includes various fields including gastroenterology, microbiology, vaccine development, and laboratory animal science. It includes clinical trials and new treatment information published four times a year.
Indian Journal of Gastroenterology: Official peer-reviewed open access publication the Indian Society of Gastroenterology
International Journal of Colorectal Disease: International Journal of Colorectal Disease - Medicine. "International Journal of Colorectal Disease" publishes novel and state-of-the-art papers which deal with the physiology and pathophysiology of diseases involving the...
Journal of Clinical Gastroenterology: Provides clinical studies and reviews, case reports, and technical expertise with a focus on gastroenterological diseases. The journal features peer-reviewed articles and clinical reviews that put the latest research and development into the context of a clinical practice.
Journal of Gastroenterology: Journal of Gastroenterology - New & Forthcoming Titles. The Journal of Gastroenterology, which is the official publication of the Japanese Society of Gastroenterology, publishes original papers, case reports, reports of multi-ce...
Journal of Gastroenterology and Hepatology Aims and Scope: Journal of Gastroenterology and Hepatology: journal information, contents lists and abstracts on the Blackwell Publishing website.
Journal of Hepato-Biliary-Pancreatic Surgery: Journal of Hepato-Biliary-Pancreatic Surgery - Surgery. The Journal of Hepato-Biliary-Pancreatic Surgery is the official journal of the Japanese Society of Hepato-Biliary-Pancreatic Surgery, the Asian Society of Hepato-Biliary-Pancr...
Journal of Pediatric Gastroenterology and Nutrition: Official journal of the European Society of Paediatric Gastroenterology, Hepatology, and Nutrition, and the North American Society for Pediatric Gastroenterology and Nutrition.
Neurogastroenterology and Motility: Neurogastroenterology and Motility: journal information, contents lists and abstracts on the Blackwell Publishing website.
New England Journal of Medicine: Gastroenterology: The Gastroenterology collection covers topics such as Helicobacter pylori, pancreatitis, and gastroenteritis and includes research articles, case reports, reviews, and editorial commentary.
Nutrition Bulletin: Nutrition Bulletin: journal information, contents lists and abstracts on the Blackwell Publishing website.
Romanian Journal of Gastroenterology: Publishes original papers, editorials and short communications on practice and experimental and clinical research.
Scandinavian Journal of Gastroenterology: International medical research in gastroenterology.
Surgical Endoscopy: Surgical Endoscopy - Surgery. Surgical Endoscopy represents the surgical aspects of interventional endoscopy, ultrasound, and other techniques in the fields of gastroenterology, obstetrics, gynecology, and urology, as well as gastro...
The Canadian Journal of Gastroenterology: Official journal of the Canadian Association of Gastroenterology and contains original papers, controlled clinical trials, review articles concerning the alimentary tract and the liver.
World of Medicine: Journals' Collection - Gastroenterology - Links to journals online PubMed abstracts.
This directory is based on the Open Directory and may have been modified