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Herbs at a Glance Update: Black Cohosh
Mon, 01 Dec 2008 09:41:27 -0500
This fact sheet provides basic information about the black cohosh—common names, uses, potential side effects, and resources for more information. Black cohosh, a member of the buttercup family, is a plant native to North America. It was used in Native American medicine and was a home remedy in 19th-century America.What It Is Used ForBlack cohosh has a history of use for rheumatism (arthritis and muscle pain) but has been used more recently to treat hot flashes, night sweats, vaginal dryness, and other symptoms that can occur during menopause.Black cohosh has also been used for menstrual irregularities and premenstrual syndrome, and to induce labor.
December 1 Is World AIDS Day
Wed, 26 Nov 2008 14:20:34 -0500
AIDS (acquired immunodeficiency syndrome) is caused by the human immunodeficiency virus, or HIV. By killing or damaging cells of the body's immune system, HIV progressively destroys the body's ability to fight infections and certain cancers. These infections are caused by viruses or bacteria that usually do not make healthy people sick.Many people infected with HIV or living with AIDS may be considering the use of complementary and alternative medicine (CAM) to boost their immune system; treat complications of disease; or cope with side effects of conventional medications.
Ginkgo Evaluation of Memory (GEM) Study Fails To Show Benefit in Preventing Dementia in the Elderly
Tue, 18 Nov 2008 17:24:53 -0500
In a study published in the Journal of the American Medical Association, 240 milligrams per day of the dietary supplement Ginkgo biloba was found to be ineffective in reducing the development of dementia and Alzheimer's disease in older people. Researchers led by Steven T. DeKosky, M.D., conducted the trial known as the Ginkgo Evaluation of Memory (GEM) study at four clinical sites over the course of 8 years. GEM is the largest clinical trial ever to evaluate ginkgo's effect on the occurrence of dementia.Press Release—summary of results of the studyQuestions and Answers—detailed background information on the study
Evidence-based Complementary and Alternative Medicine - current issue
eCAM: An Emerging Linkage with Ethnopharmacology?
Cooper, E. L. Fri, 21 Nov 2008 00:00:00 -0000
Second World Ayurveda Congress (Theme: Ayurveda for the Future)--Inaugural Address: Part III
Mashelkar, R. A. Fri, 21 Nov 2008 00:00:00 -0000
A Review of CAM for Procedural Pain in Infancy: Part I. Sucrose and Non-nutritive Sucking
Tsao, J. C. I., Evans, S., Meldrum, M., Altman, T., Zeltzer, L. K. Fri, 21 Nov 2008 00:00:00 -0000
There is increasing concern regarding the number of painful medical procedures that infants must undergo and the potential risks of alleviating infant pain with conventional pharmacologic agents. This article is Part I of a two-part series that aims to provide an overview of the literature on complementary and alternative (CAM) approaches for pain and distress related to medical procedures among infants up to six weeks of age. The focus of this article is a review of the empirical literature on sucrose with or without non-nutritive sucking (NNS) for procedural pain in infancy. Computerized databases were searched for relevant studies including prior reviews and primary trials. The most robust evidence was found for the analgesic effects of sucrose with or without NNS on minor procedural pain in healthy full-term infants. Despite some methodological weaknesses, the literature to date supports the use of sucrose, NNS and other sweetened solutions for the management of procedural pain in infancy.
BMC Complementary and Alternative Medicine - Latest articles
Petiveria alliacea extracts uses multiple mechanisms to inhibit growth of human and mouse tumoral cells
Claudia P Uruena, Claudia Cifuentes, Diana M Castaneda, Amparo D Arango, Punit Kaur, Alexzander A Asea and Susana Fiorentino Tue, 18 Nov 2008 00:00:00 -0000
Background: There is ethnopharmacological evidence that Petiveria alliacea can have antitumor activity; however, the mechanism of its cytotoxic activity is not well understood. We assessed multiple in vitro biological activities of an ethyl acetate soluble plant fraction over several tumor cell lines. Methods: Tumor cell lines were evaluated using the following tests: trypan blue exclusion test, MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide], flow cytometry, cytoskeleton organization analysis, cell cycle, mitochondria membrane depolarization, clonogenicity test, DNA fragmentation test and differential protein expression by HPLC-Chip/MS analysis. F4 fraction characterization was made by HPLC-MS. Results: Petiveria alliacea fraction characterized by de-replication was found to alter actin cytoskeleton organization, induce G2 cell cycle arrest and cause apoptotic cell death in a mitochondria independent way. In addition, we found down regulation of cytoskeleton, chaperone, signal transduction proteins, and proteins involved in metabolic pathways. Finally up regulation of proteins involved in translation and intracellular degradation was also observed. Conclusions: The results of this study indicate that Petiveria alliacea exerts multiple biological activities in vitro consistent with cytotoxicity. Further studies in animal models are needed but Petiveria alliacea appears to be a good candidate to be used as an antitumor agent.
Induction of apoptosis of human primary osteoclasts treated with extracts from the medicinal plant Emblica officinalis
Letizia Penolazzi, Ilaria Lampronti, Monica Borgatti, Mahmud Tareq Hassan Khan, Margherita Zennaro, Roberta Piva and Roberto Gambari Thu, 30 Oct 2008 00:00:00 -0000
Background: Osteoclasts (OCs) are involved in rheumatoid arthritis and in several pathologies associated with bone loss. Recent results support the concept that some medicinal plants and derived natural products are of great interest for developing therapeutic strategies against bone disorders, including rheumatoid arthritis and osteoporosis. In this study we determined whether extracts of Emblica officinalis fruits display activity of possible interest for the treatment of rheumatoid arthritis and osteoporosis by activating programmed cell death of human primary osteoclasts. Methods: The effects of extracts from Emblica officinalis on differentiation and survival of human primary OCs cultures obtained from peripheral blood were determined by tartrate-acid resistant acid phosphatase (TRAP)-positivity and colorimetric MTT assay. The effects of Emblica officinalis extracts on induction of OCs apoptosis were studied using TUNEL and immunocytochemical analysis of FAS receptor expression. Finally, in vitro effects of Emblica officinalis extracts on NF-kB transcription factor activity were determined by gel shift experiments. Results: Extracts of Emblica officinalis were able to induce programmed cell death of mature OCs, without altering, at the concentrations employed in our study, the process of osteoclastogenesis. Emblica officinalis increased the expression levels of Fas, a critical member of the apoptotic pathway. Gel shift experiments demonstrated that Emblica officinalis extracts act by interfering with NF-kB activity, a transcription factor involved in osteoclast biology. The data obtained demonstrate that Emblica officinalis extracts selectively compete with the binding of transcription factor NF-kB to its specific target DNA sequences. This effect might explain the observed effects of Emblica officinalis on the expression levels of interleukin-6, a NF-kB specific target gene. Conclusion: Induction of apoptosis of osteoclasts could be an important strategy both in interfering with rheumatoid arthritis complications of the bone skeleton leading to joint destruction, and preventing and reducing osteoporosis. Accordingly, we suggest the application of Emblica officinalis extracts as an alternative tool for therapy applied to bone diseases.
TCMGeneDIT: a database for associated traditional Chinese medicine, gene and disease information using text mining
Yu-Ching Fang, Hsuan-Cheng Huang, Hsin-Hsi Chen and Hsueh-Fen Juan Tue, 14 Oct 2008 00:00:00 -0000
Background: Traditional Chinese Medicine (TCM), a complementary and alternative medical system in Western countries, has been used to treat various diseases over thousands of years in East Asian countries. In recent years, many herbal medicines were found to exhibit a variety of effects through regulating a wide range of gene expressions or protein activities. As available TCM data continue to accumulate rapidly, an urgent need for exploring these resources systematically is imperative, so as to effectively utilize the large volume of literature. Methods: TCM, gene, disease, biological pathway and protein-protein interaction information were collected from public databases. For association discovery, the TCM names, gene names, disease names, TCM ingredients and effects were used to annotate the literature corpus obtained from PubMed. The concept to mine entity associations was based on hypothesis testing and collocation analysis. The annotated corpus was processed with natural language processing tools and rule-based approaches were applied to the sentences for extracting the relations between TCM effecters and effects. Results: We developed a database, TCMGeneDIT, to provide association information about TCMs, genes, diseases, TCM effects and TCM ingredients mined from vast amount of biomedical literature. Integrated protein-protein interaction and biological pathways information are also available for exploring the regulations of genes associated with TCM curative effects. In addition, the transitive relationships among genes, TCMs and diseases could be inferred through the shared intermediates. Furthermore, TCMGeneDIT is useful in understanding the possible therapeutic mechanisms of TCMs via gene regulations and deducing synergistic or antagonistic contributions of the prescription components to the overall therapeutic effects. The database is now available at http://tcm.lifescience.ntu.edu.tw/. Conclusion: TCMGeneDIT is a unique database that offers diverse association information on TCMs. This database integrates TCMs with biomedical studies that would facilitate clinical research and elucidate the possible therapeutic mechanisms of TCMs and gene regulations.
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Herbs at a Glance Update: Black Cohosh
Mon, 01 Dec 2008 09:41:27 -0500
This fact sheet provides basic information about the black cohosh—common names, uses, potential side effects, and resources for more information. Black cohosh, a member of the buttercup family, is a plant native to North America. It was used in Native American medicine and was a home remedy in 19th-century America.What It Is Used ForBlack cohosh has a history of use for rheumatism (arthritis and muscle pain) but has been used more recently to treat hot flashes, night sweats, vaginal dryness, and other symptoms that can occur during menopause.Black cohosh has also been used for menstrual irregularities and premenstrual syndrome, and to induce labor.
December 1 Is World AIDS Day
Wed, 26 Nov 2008 14:20:34 -0500
AIDS (acquired immunodeficiency syndrome) is caused by the human immunodeficiency virus, or HIV. By killing or damaging cells of the body's immune system, HIV progressively destroys the body's ability to fight infections and certain cancers. These infections are caused by viruses or bacteria that usually do not make healthy people sick.Many people infected with HIV or living with AIDS may be considering the use of complementary and alternative medicine (CAM) to boost their immune system; treat complications of disease; or cope with side effects of conventional medications.
Ginkgo Evaluation of Memory (GEM) Study Fails To Show Benefit in Preventing Dementia in the Elderly
Tue, 18 Nov 2008 17:24:53 -0500
In a study published in the Journal of the American Medical Association, 240 milligrams per day of the dietary supplement Ginkgo biloba was found to be ineffective in reducing the development of dementia and Alzheimer's disease in older people. Researchers led by Steven T. DeKosky, M.D., conducted the trial known as the Ginkgo Evaluation of Memory (GEM) study at four clinical sites over the course of 8 years. GEM is the largest clinical trial ever to evaluate ginkgo's effect on the occurrence of dementia.Press Release—summary of results of the studyQuestions and Answers—detailed background information on the study
Evidence-based Complementary and Alternative Medicine - current issue
eCAM: An Emerging Linkage with Ethnopharmacology?
Cooper, E. L. Fri, 21 Nov 2008 00:00:00 -0000
Second World Ayurveda Congress (Theme: Ayurveda for the Future)--Inaugural Address: Part III
Mashelkar, R. A. Fri, 21 Nov 2008 00:00:00 -0000
A Review of CAM for Procedural Pain in Infancy: Part I. Sucrose and Non-nutritive Sucking
Tsao, J. C. I., Evans, S., Meldrum, M., Altman, T., Zeltzer, L. K. Fri, 21 Nov 2008 00:00:00 -0000
There is increasing concern regarding the number of painful medical procedures that infants must undergo and the potential risks of alleviating infant pain with conventional pharmacologic agents. This article is Part I of a two-part series that aims to provide an overview of the literature on complementary and alternative (CAM) approaches for pain and distress related to medical procedures among infants up to six weeks of age. The focus of this article is a review of the empirical literature on sucrose with or without non-nutritive sucking (NNS) for procedural pain in infancy. Computerized databases were searched for relevant studies including prior reviews and primary trials. The most robust evidence was found for the analgesic effects of sucrose with or without NNS on minor procedural pain in healthy full-term infants. Despite some methodological weaknesses, the literature to date supports the use of sucrose, NNS and other sweetened solutions for the management of procedural pain in infancy.
BMC Complementary and Alternative Medicine - Latest articles
Petiveria alliacea extracts uses multiple mechanisms to inhibit growth of human and mouse tumoral cells
Claudia P Uruena, Claudia Cifuentes, Diana M Castaneda, Amparo D Arango, Punit Kaur, Alexzander A Asea and Susana Fiorentino Tue, 18 Nov 2008 00:00:00 -0000
Background: There is ethnopharmacological evidence that Petiveria alliacea can have antitumor activity; however, the mechanism of its cytotoxic activity is not well understood. We assessed multiple in vitro biological activities of an ethyl acetate soluble plant fraction over several tumor cell lines. Methods: Tumor cell lines were evaluated using the following tests: trypan blue exclusion test, MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide], flow cytometry, cytoskeleton organization analysis, cell cycle, mitochondria membrane depolarization, clonogenicity test, DNA fragmentation test and differential protein expression by HPLC-Chip/MS analysis. F4 fraction characterization was made by HPLC-MS. Results: Petiveria alliacea fraction characterized by de-replication was found to alter actin cytoskeleton organization, induce G2 cell cycle arrest and cause apoptotic cell death in a mitochondria independent way. In addition, we found down regulation of cytoskeleton, chaperone, signal transduction proteins, and proteins involved in metabolic pathways. Finally up regulation of proteins involved in translation and intracellular degradation was also observed. Conclusions: The results of this study indicate that Petiveria alliacea exerts multiple biological activities in vitro consistent with cytotoxicity. Further studies in animal models are needed but Petiveria alliacea appears to be a good candidate to be used as an antitumor agent.
Induction of apoptosis of human primary osteoclasts treated with extracts from the medicinal plant Emblica officinalis
Letizia Penolazzi, Ilaria Lampronti, Monica Borgatti, Mahmud Tareq Hassan Khan, Margherita Zennaro, Roberta Piva and Roberto Gambari Thu, 30 Oct 2008 00:00:00 -0000
Background: Osteoclasts (OCs) are involved in rheumatoid arthritis and in several pathologies associated with bone loss. Recent results support the concept that some medicinal plants and derived natural products are of great interest for developing therapeutic strategies against bone disorders, including rheumatoid arthritis and osteoporosis. In this study we determined whether extracts of Emblica officinalis fruits display activity of possible interest for the treatment of rheumatoid arthritis and osteoporosis by activating programmed cell death of human primary osteoclasts. Methods: The effects of extracts from Emblica officinalis on differentiation and survival of human primary OCs cultures obtained from peripheral blood were determined by tartrate-acid resistant acid phosphatase (TRAP)-positivity and colorimetric MTT assay. The effects of Emblica officinalis extracts on induction of OCs apoptosis were studied using TUNEL and immunocytochemical analysis of FAS receptor expression. Finally, in vitro effects of Emblica officinalis extracts on NF-kB transcription factor activity were determined by gel shift experiments. Results: Extracts of Emblica officinalis were able to induce programmed cell death of mature OCs, without altering, at the concentrations employed in our study, the process of osteoclastogenesis. Emblica officinalis increased the expression levels of Fas, a critical member of the apoptotic pathway. Gel shift experiments demonstrated that Emblica officinalis extracts act by interfering with NF-kB activity, a transcription factor involved in osteoclast biology. The data obtained demonstrate that Emblica officinalis extracts selectively compete with the binding of transcription factor NF-kB to its specific target DNA sequences. This effect might explain the observed effects of Emblica officinalis on the expression levels of interleukin-6, a NF-kB specific target gene. Conclusion: Induction of apoptosis of osteoclasts could be an important strategy both in interfering with rheumatoid arthritis complications of the bone skeleton leading to joint destruction, and preventing and reducing osteoporosis. Accordingly, we suggest the application of Emblica officinalis extracts as an alternative tool for therapy applied to bone diseases.
TCMGeneDIT: a database for associated traditional Chinese medicine, gene and disease information using text mining
Yu-Ching Fang, Hsuan-Cheng Huang, Hsin-Hsi Chen and Hsueh-Fen Juan Tue, 14 Oct 2008 00:00:00 -0000
Background: Traditional Chinese Medicine (TCM), a complementary and alternative medical system in Western countries, has been used to treat various diseases over thousands of years in East Asian countries. In recent years, many herbal medicines were found to exhibit a variety of effects through regulating a wide range of gene expressions or protein activities. As available TCM data continue to accumulate rapidly, an urgent need for exploring these resources systematically is imperative, so as to effectively utilize the large volume of literature. Methods: TCM, gene, disease, biological pathway and protein-protein interaction information were collected from public databases. For association discovery, the TCM names, gene names, disease names, TCM ingredients and effects were used to annotate the literature corpus obtained from PubMed. The concept to mine entity associations was based on hypothesis testing and collocation analysis. The annotated corpus was processed with natural language processing tools and rule-based approaches were applied to the sentences for extracting the relations between TCM effecters and effects. Results: We developed a database, TCMGeneDIT, to provide association information about TCMs, genes, diseases, TCM effects and TCM ingredients mined from vast amount of biomedical literature. Integrated protein-protein interaction and biological pathways information are also available for exploring the regulations of genes associated with TCM curative effects. In addition, the transitive relationships among genes, TCMs and diseases could be inferred through the shared intermediates. Furthermore, TCMGeneDIT is useful in understanding the possible therapeutic mechanisms of TCMs via gene regulations and deducing synergistic or antagonistic contributions of the prescription components to the overall therapeutic effects. The database is now available at http://tcm.lifescience.ntu.edu.tw/. Conclusion: TCMGeneDIT is a unique database that offers diverse association information on TCMs. This database integrates TCMs with biomedical studies that would facilitate clinical research and elucidate the possible therapeutic mechanisms of TCMs and gene regulations.

Sites:
Homeopathy Home: The Net's premier site for all things homeopathic - a world directory, commercial and other web links and a full reference library.A Dictionary of Practical Materia Medica: Alphabetized online index. A Classic Homeopathic Guide- By John Henry Clarke, M.D. Presented by Médi-T. Preface written by Dr. Clarke on July 4, 1900.
ABC Homeopathy: Complete homeopathy site. With directory, comprehensive homeopathy store and homeopathy remedy finder which suggests homeopathic remedies from over 64,000 symptoms and 650 remedies
Ask Dr.Shah.com: Ask your health question to Dr.Shah for an homeopathic medical advice. A free homeopathy health service with online treatment option with Dr.Shah from India.
Boenninghausen Shareware Repertory: Homöopathie Programm als Shareware Repertorium nach der Methode von Boenninghausen Homeopathy Repertory Shareware Software BoennRep, Homöopathie Programm als Shareware Repertorium nach der Methode von Boenninghausen Homeopathy Repertory Shareware Software BoennRep
Classical Homeopathy: A pioneer homeopathy website on the net offering FAQs, treatment plans, journals, training course, software, etc.
Dr Andrew Lockie - Homeopathic Services: Dr Andrew Lockie homeopathic infromation services covers a breadth of information on homeopathy and complementary medicine.
Dr. Ramakrishnan: Honorary Homeopathic Physician to the President of India. An internationally known medical doctor from India. He travels the world lecturing on homeopathy and treating difficult cases.
Dr.K.NELSON: Dr.Nelson Kochappavu's thesis, Nature-Natural-Curentu of Natural Medicine, emphasis the need of a cure in the form of natural sources, food as medicine.
DrPradhan.com: A comprehensive web site, which provides all information on Homeopathy. The information is in the form of frequently asked questions and articles on Homeopathy and Disease Management. The site also explains disease condition in simple English. Quality site for Homeopathic Management., A homoeopat...
Hahnemann Centre for Heilkunst: Information about the Hahnemann Center for Heilkunst, a not-for-profit, federally-registered educational institution run by the Hahemann Center Trust
Hahnemann's Advanced Methods by David Little: H.O.E. (Homoeopathic Online Education) is an organization founded by David Little. David has been practicing Homoeopathy for the past 30 years. A collection of his articles and other educational information are the core part of this site. Our goal is to provide valuable knowledge of the true meth...
High Dilutions: High dilutions site, Site des hautes dilutions.
Homeocases.org: A database of cured cases, articles, remedy description, materia medica and information about homeopathy.
HomeoInfo - Classical Homeopathy: A non-commercial educational site and reference to all aspects of classical homeopathy. Extensive information.
Homeomiracles: Wonderful cures on incurable diseases with photos, Documentations, audio video files with diet, online treatment chat and videoconference
Homeopathic Medicine for Animals and Humans: Best Links: Best links to Homeopathic Medicine Websites and databases for medical and veterinary professionals in human and animal medicine
Homeopaths: Dedicated to providing on-line services to homeopaths and individuals wishing to use homeopathy.
Homeopathy - The Skeptic's Dictionary: Prof. Robert Todd Carroll article on the homeopathy industry.
Homeopathy and Disaster Help: Homeopathy and it uses. Specific Use of homeopathy in disasters and emergencies. Disaster Assitance. Massachusetts Senate Race for David Cleveland
Homeopathy and Natural Health - N.Marar Registered Homeopath: Welcome to Homeopathy and Natural Health Care with Mr. N. Marar - your one stop guide to homeopathy, natural health and healing ...
Homeopathy and Vaccination: a way to cure serious side effects of vaccinations by homeopathy and a new long-term homeopathic treatment called 'Inspiring Homeopathy'
Homeopathy Australia: A web site providing information on homeopathy, and other related healtlh matters, for Australians.
Homeopathy Boiron: The homeopathy website of the Boiron Group, the leading laboratory in homeopathy, provides you with information about: homeopathy, boiron, boiron group
Homeopathy for Women's and Children's Health: Homeopathic medicine and how it relates to various women's and children's health issues.
Homeopathy from WHN: Homeopathy software for the professional and student, plus in-depth articles and features. RADAR homeopathic software and Encyclopedia Homeopathica, plus an online homeopathy book store.
Homeopathy Today News: The National Center for Homeopathy is a non-profit membership organization dedicated to making homeopathy accessible to the public.
Homeopathy: Modern Medicine of the 21st Century: A homoeopathy website from India for lay-people as well as for the professionals. Offers FAQs, online consultation, journal, and courses. Wide range of resources and information.
Hpathy: Homeopathy for Everyone! World's No.1 site for Homeopathic Medicine, Homeopathy, Books, Information, Homeopathic Remedies, Software, Doctors and much more!
Julian Winston: Julian Winston's personal web site.
Naturally You! - Homeopathic Solutions: Robert Lee Dalpé, ND offers quality Classical Homeopathic Therapy, instruction and expert consulting via the Internet, remedies for new, epidemic and singular diseases, materia medica essences, independent homeopathic research for: A.I.D.S., S.A.R.S., T.S.E. Diseases such as C.J.D. and Mad Cow D...
Pediatric Oncall: Find out more about homoepathy and its use in various childhood diseases at www.pediatriconcall.com
Peter Schneider - Isopathic/Homeopathic: Information about isopathic-homeopathic therapy in humans and animals, pleomorphism, Enderlein
Saibaba Online Alternative Health Solutions: Offers a list of conditions and diseases along with remedies listed there to see which covers your symptoms most. Also a list of suppliers, FAQs and a message board. Also contact details for assistance with homeopathy.
The Potentiation Problem: How can one understand the potentizing of homeopathic medicines from an anthroposophical perspective
The Ultimate Guide to Homeopathy: The Net's premier site for all things homeopathic - a world directory, commercial and other web links
