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NCCAM Featured Content

Ginkgo Evaluation of Memory (GEM) Study Fails To Show Benefit in Preventing Dementia in the Elderly
Tue, 18 Nov 2008 17:24:53 -0500
In a study published in the Journal of the American Medical Association, 240 milligrams per day of the dietary supplement Ginkgo biloba was found to be ineffective in reducing the development of dementia and Alzheimer's disease in older people. Researchers led by Steven T. DeKosky, M.D., conducted the trial known as the Ginkgo Evaluation of Memory (GEM) study at four clinical sites over the course of 8 years. GEM is the largest clinical trial ever to evaluate ginkgo's effect on the occurrence of dementia.Press Release—summary of results of the studyQuestions and Answers—detailed background information on the study
Massage Therapy May Ease Pain and Improve Mood in Advanced Cancer Patients
Tue, 11 Nov 2008 13:34:20 -0500
People with advanced cancer often experience pain that causes physical and emotional distress, which leads to a decrease in functional ability and quality of life. Symptom relief is an important part of end-of-life care, and small studies have suggested that massage therapy may benefit people with advanced cancer.In a study funded in part by NCCAM, researchers investigated the benefits of massage versus simple touch therapy (placing both hands on specific body sites) in patients with advanced cancer. This multisite study—conducted at 15 U.S. hospices in the Population-based Palliative Care Research Network—included 380 participants with advanced cancer who were experiencing moderate-to-severe pain. Participants were randomly assigned to receive six 30-minute treatment sessions of either massage or simple touch therapy over a 2-week period.
CAM and Hepatitis C: A Focus on Herbal Supplements
Tue, 04 Nov 2008 11:16:44 -0500
Hepatitis C, a liver disease caused by a virus, is usually chronic (long-lasting), with symptoms ranging from mild (or even none) to severe. Conventional medical treatments are available for hepatitis C; however, some people also try complementary and alternative medicine (CAM) therapies, especially herbal supplements. This fact sheet provides basic information on hepatitis C, summarizes scientific research on the effectiveness and safety of selected supplements, and suggests sources for additional information.Key Points No CAM treatment has yet been proven effective for treating hepatitis C or its complications. It is important not to replace conventional medical therapy for hepatitis C with an unproven CAM therapy. Tell your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

Evidence-based Complementary and Alternative Medicine - current issue

eCAM: Early Harvest
Cooper, E. L. Thu, 04 Sep 2008 00:00:00 -0000

Second World Ayurveda Congress (Theme: Ayurveda for the Future)--Inaugural Address: Part II
Mashelkar, R. A. Thu, 04 Sep 2008 00:00:00 -0000

Can Vitex Agnus Castus be Used for the Treatment of Mastalgia? What is the Current Evidence?
Carmichael, A.R. Thu, 04 Sep 2008 00:00:00 -0000
There have been many treatments suggested for the management of mastalgia; one of these is the fruit extract of Vitex Agnus castus L. commonly known as Agnus castus, an extract of a deciduous shrub native to Mediterranean Europe and Central Asia. It is postulated that A. castus suppresses the stress-induced latent hyperprolactinemia which is a release of supra-physiological levels of prolactin in some patients in response to stressful stimuli. It is postulated that A. castus could be effective in the treatment of cyclical mastalgia by inhibiting the release of excess prolactin by blocking Dopamine-2 receptor type on pituitary. The adverse events following A. castus treatment are mild and reversible. The aim of this review is assess the efficacy of A. castus in the treatment of mastalgia. Data from randomized and non-randomized studies regarding the efficacy and safety of A. castus is reviewed in a systematic fashion. It is concluded that A. castus can be considered as an efficient alternative phytotherapeutic agent in the treatment of mastalgia.

BMC Complementary and Alternative Medicine - Latest articles

Petiveria alliacea extracts uses multiple mechanisms to inhibit growth of human and mouse tumoral cells
Claudia P Uruena, Claudia Cifuentes, Diana M Castaneda, Amparo D Arango, Punit Kaur, Alexzander A Asea and Susana Fiorentino Tue, 18 Nov 2008 00:00:00 -0000
Background: There is ethnopharmacological evidence that Petiveria alliacea can have antitumor activity; however, the mechanism of its cytotoxic activity is not well understood. We assessed multiple in vitro biological activities of an ethyl acetate soluble plant fraction over several tumor cell lines. Methods: Tumor cell lines were evaluated using the following tests: trypan blue exclusion test, MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide], flow cytometry, cytoskeleton organization analysis, cell cycle, mitochondria membrane depolarization, clonogenicity test, DNA fragmentation test and differential protein expression by HPLC-Chip/MS analysis. F4 fraction characterization was made by HPLC-MS. Results: Petiveria alliacea fraction characterized by de-replication was found to alter actin cytoskeleton organization, induce G2 cell cycle arrest and cause apoptotic cell death in a mitochondria independent way. In addition, we found down regulation of cytoskeleton, chaperone, signal transduction proteins, and proteins involved in metabolic pathways. Finally up regulation of proteins involved in translation and intracellular degradation was also observed. Conclusions: The results of this study indicate that Petiveria alliacea exerts multiple biological activities in vitro consistent with cytotoxicity. Further studies in animal models are needed but Petiveria alliacea appears to be a good candidate to be used as an antitumor agent.
Induction of apoptosis of human primary osteoclasts treated with extracts from the medicinal plant Emblica officinalis
Letizia Penolazzi, Ilaria Lampronti, Monica Borgatti, Mahmud Tareq Hassan Khan, Margherita Zennaro, Roberta Piva and Roberto Gambari Thu, 30 Oct 2008 00:00:00 -0000
Background: Osteoclasts (OCs) are involved in rheumatoid arthritis and in several pathologies associated with bone loss. Recent results support the concept that some medicinal plants and derived natural products are of great interest for developing therapeutic strategies against bone disorders, including rheumatoid arthritis and osteoporosis. In this study we determined whether extracts of Emblica officinalis fruits display activity of possible interest for the treatment of rheumatoid arthritis and osteoporosis by activating programmed cell death of human primary osteoclasts. Methods: The effects of extracts from Emblica officinalis on differentiation and survival of human primary OCs cultures obtained from peripheral blood were determined by tartrate-acid resistant acid phosphatase (TRAP)-positivity and colorimetric MTT assay. The effects of Emblica officinalis extracts on induction of OCs apoptosis were studied using TUNEL and immunocytochemical analysis of FAS receptor expression. Finally, in vitro effects of Emblica officinalis extracts on NF-kB transcription factor activity were determined by gel shift experiments. Results: Extracts of Emblica officinalis were able to induce programmed cell death of mature OCs, without altering, at the concentrations employed in our study, the process of osteoclastogenesis. Emblica officinalis increased the expression levels of Fas, a critical member of the apoptotic pathway. Gel shift experiments demonstrated that Emblica officinalis extracts act by interfering with NF-kB activity, a transcription factor involved in osteoclast biology. The data obtained demonstrate that Emblica officinalis extracts selectively compete with the binding of transcription factor NF-kB to its specific target DNA sequences. This effect might explain the observed effects of Emblica officinalis on the expression levels of interleukin-6, a NF-kB specific target gene. Conclusions: Induction of apoptosis of osteoclasts could be an important strategy both in interfering with rheumatoid arthritis complications of the bone skeleton leading to joint destruction, and preventing and reducing osteoporosis. Accordingly, we suggest the application of Emblica officinalis extracts as an alternative tool for therapy applied to bone diseases.
TCMGeneDIT: a database for associated traditional Chinese medicine, gene and disease information using text mining
Yu-Ching Fang, Hsuan-Cheng Huang, Hsin-Hsi Chen and Hsueh-Fen Juan Tue, 14 Oct 2008 00:00:00 -0000
Background: Traditional Chinese Medicine (TCM), a complementary and alternative medical system in Western countries, has been used to treat various diseases over thousands of years in East Asian countries. In recent years, many herbal medicines were found to exhibit a variety of effects through regulating a wide range of gene expressions or protein activities. As available TCM data continue to accumulate rapidly, an urgent need for exploring these resources systematically is imperative, so as to effectively utilize the large volume of literature. Methods: TCM, gene, disease, biological pathway and protein-protein interaction information were collected from public databases. For association discovery, the TCM names, gene names, disease names, TCM ingredients and effects were used to annotate the literature corpus obtained from PubMed. The concept to mine entity associations was based on hypothesis testing and collocation analysis. The annotated corpus was processed with natural language processing tools and rule-based approaches were applied to the sentences for extracting the relations between TCM effecters and effects. Results: We developed a database, TCMGeneDIT, to provide association information about TCMs, genes, diseases, TCM effects and TCM ingredients mined from vast amount of biomedical literature. Integrated protein-protein interaction and biological pathways information are also available for exploring the regulations of genes associated with TCM curative effects. In addition, the transitive relationships among genes, TCMs and diseases could be inferred through the shared intermediates. Furthermore, TCMGeneDIT is useful in understanding the possible therapeutic mechanisms of TCMs via gene regulations and deducing synergistic or antagonistic contributions of the prescription components to the overall therapeutic effects. The database is now available at http://tcm.lifescience.ntu.edu.tw/. Conclusion: TCMGeneDIT is a unique database that offers diverse association information on TCMs. This database integrates TCMs with biomedical studies that would facilitate clinical research and elucidate the possible therapeutic mechanisms of TCMs and gene regulations.

 
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Alexander Technique - Find a Teacher or Course: Information on finding a teacher of the Alexander Technique anywhere in the world.

Aimingup.com: Private and group classes with Kate Kobak in New York City.

Alexander Technique: Glenn Swifts website contains information about

Alexander Technique: La Tecnica Alexander es un metodo para prevenir tensiones y malas posturas que producen dolor de espalda y cuello, problemas de voz, lesiones musculares, ansiedad, inseguridad y estres

Alexander Technique: Reduce symptoms of tension, stress, and strain. Learn to develop and maintain flexibility and energy for everyday and skilled activities like playing music and sports

Alexander Technique: Lawrence Smith, certified Alexander Technique teacher based in Le Plateau Mont-Royal Montreal, Quebec (Canada)

Alexander Technique: Certified teacher Rosemary Moone offers sessions at several locations in Cork, Ireland. Includes FAQ and class details.

Alexander Technique Associates: Alexander Technique Associates. In depth information about the Alexander Technique. Lessons, classes and courses in Australia. Finding a Teacher of the Alexander Technique.

Alexander Technique Atlantic: Halifax, Nova Scotia. Lessons and courses with Tisha Miller and David Langstroth.

Alexander Technique Center: Lessons, workshops, and teacher training in the Washington, DC area.

Alexander Technique Center New England: Learn how to prevent unconscious habits of tension, malcoordination, and emotional reaction. Enhance locomotor skill and coordination. An education in the use of your self. A method for integrating mind and body in action. Prevent unconscious habits of misuse of your self. The Alexander Technique...

Alexander Technique Centre (ATC) Kyoto: Alexander lessons and workshops with certified teachers.

Alexander Technique Centre Ireland: Offers a list of teachers in the country, as well as background information.

Alexander Technique for Performance and Development: Lessons and classes with Tom Vasiliades, certified teacher, in New York City.

Alexander Technique in Auckland, New Zealand: Jann and Ian McMichael are certified teachers.

Alexander Technique in Manhattan, Brooklyn, and Long Island: Leland Vall , Alexander Technique teacher in New York, Queens & Long Island. Improve back pain, tension, asthma, repetitive strain injury, posture, headache, and stress.

Alexander Technique in Newton, MA: Alexander Technique teaches how to improve posture, balance, poise and flexibility by unlearning habits causing stiffness, tension and pain

Alexander Technique in Northern California: Nora Nausbaum is a certified teacher of the Alexander Technique, an educational method that increases understanding of our balance, coordination, posture and poise.

Alexander Technique in Oceanside, CA: Sally Shallenberg teaches the Alexander Technique in Oceanside (San Diego county), California.

Alexander Technique in Vancouver, Canada: Lessons and classes with Marc Speyer

Alexander Technique in West Chester, Pennsylvania: Robert Bedford, a teacher specializing in working with musicians.

Alexander Technique Institute: Alexander Technique private lessons and teaching training

Alexander Technique Melbourne: Paul Cook Alexander Technique offers professionalAlexander learning in Melbourne. For posture, back pain and other conditions.

Alexander Technique Pittsburgh: Lessons, classes, and workshops with Lonna Wilkerson and Lisa Levinson. Features photographs, FAQ, class schedules, and biographies.

Alexander Technique San Francisco: Fumi Sasa offers classes in California, New Mexico, and Japan, with program details and testimonials.

Alexander Technique Studio: Lessons in the Alexander Technique can restore a natural grace and ease of movement, reduce pain and relieve stress.

Alexander Technique Sydney: Alexander Technique teacher Mark Bennie offers lessons in Kirribilli, North Sydney. Helps back, neck and joint pain, carpal tunnel syndrome, headaches, posture and breathing.

Alexander Technique Teachers of Greater Washington: A coalition of instructors in the District of Columbia, USA. Includes state lists and workshop details.

Alexander Technique Vancouver: Lessons with Penny Silver.

Alexander Technique: Tools for Change: Private Alexander lessons & group classes in NYC. Annual workshop in Greece combines Alexander, Greek Myth and movement improvisation. Movement re-education promoting flexibility, ease, coordination & pleasure. Groups can be designed for specific audience

Alexander Techworks: Private and group instruction in the Alexander Technique for Actors, Athletes, & Performers to improve posture, movement, vocal and performance techniques.

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Anne-René Lawton: Certified teacher and dance instructor offers classes in New York, with biography and photographs.

Ariel Weiss Holyst: A certified teacher of the Alexander Technique with private practices in Center City Philadelphia and Delaware County locations and 15 years experience teaching students of all ages and at all levels addressing a wide range of activities including performance coaching (dance, theater, opera), inj...

Bio-Ergonomics / Alexander Technique: The BEAT is a system of bio-mechanics that teaches people to put ergonomic principles into practice.

Centre for Personal Performance Enhancement: The Centre for Personal Performance Enhancement helps its clients to fulfill their potential in any chosen field.

Eco Somatics: Alex Nicolson teaches the Alexander Technique since 1986. What is the Alexander Technique? Call Alex Sydney 612 9969 9100 a.h. 612 9953 1076 for an appointment. Has a black belt in Aikido and a masters degree in Social Ecology MAppSc. Sydney Alexander Technique Sydney

Freedom in Action: Lessons with Michael Stenning and Leonie John, certified teachers. Canberra, Australia.

George I. Lister and Sally Porter Munro: George Lister is a teacher of the Alexander Technique and has been studying and teaching for sixteen years. Sally Munro, mezzo-soprano is a native of London, England and a graduate of the Royal Northern College of Music, Manchester, England.

Good Use of Self: Robert H. Schweitzer's Alexander Technique Teaching Website.

Integrated Motion Studio: Group or private lessons in Hadley, Massachusetts. Instructor Molly B. Johnson describes her background and provides information about the Alexander Technique.

Irish Society of Alexander Technique Teachers: all inclusive vacation package seminar coaching weiterbildung training beratung schulung

Japan Solidarity of Teachers of the Alexander Technique: Listing of several teachers in Japan.

Jeff Tessler: Certified teacher. Includes profile, details of technique and information about T'ai Chi classes.

Joan Arnold - Refining Your Posture: causes symptoms of lower back pain, Alexander Technique and Yoga

John Baron: The Alexander Technique is an educational technique that includes hands on work by a trained professional, where you learn how to release tension in the body and gain the ability to participate in all of life's activities with freedom of movement and a sense of well-being.

Linda Souza: The Alexander Technique teaches people how to become aware of habits in body movement that may be causing stress, strain and pain. Linda Souza is an Alexander Teacher who teaches in Laguna Beach, California. She teaches her students how to move with less tension, less stress, more ease and in t...

Malcolm King: Alexander Technique lessons and Singing lessons in Paris from international opera singer and teacher, Malcolm King. Solve voice, breathing, posture, coordination and general physical problems through the use of sound body principles.

Mark Josefsberg: Certified teacher offering classes in New York, and providing testimonials, background articles, and fee schedule.

Micha Rotstein: Micha Rotstein, Certified teacher (AUSTAT) offers Alexander Technique lessons in St Kilda, Melbourne. For pain relief, improved performance, better posture, well-being and self development.

Michael Hanko: Alexander Technique: the proven mind-body method for enhancing health and performance, reducing stress and pain. Learn to use your body the way Nature intended. Michael Hanko, C.T.A.T., (917) 239-0863.

Michelle Despax: Lessons with certified teacher and horsemanship instructor. Langwarrin South, Victoria, Australia.

N. Brooke Lieb: Offering services in The Alexander Technique, Personal Coaching, and ACCESS Energy Transformation.

Neils Home Studio: Lessons with Neil Schapera, certified teacher. Cincinnati, Ohio.

New York Center for the Alexander Technique: Laurie Kline and Michael Ostrow are certified teachers in Manhattan. Includes FAQ and workshop details.

Pedro de Alcantara: Pedro de Alcantara's website brings you a wide variety of resources, articles, and links about the Alexander Technique and its application to music-making, creative writing, and health. Please visit often!

Rajal Cohen: Rajal Cohen is an AmSAT certified teacher of the Alexander Technique. She helps people to unlearn harmful postural habits and tensions and to learn to move with greater comfort, efficiency and ease.

Raya Leighton: Alexander technique helps to correct posture, it can help with back, neck, knee pains etc.The treatment is holistic and individual. שיטת אלכסנדר עוזרת עם יציבה נכונה ויכול לעזור בכאבי גב, צוואר וברכיים וכו'. הטיפול הוא הולי...

Redirection: Alexander Technique: Redirection AT is an online resource dedicated to learning about the Alexander Technique. We give information on the Alexander Technique, method for movement re-education which reduces pain and tension while improving freedom of movement. We also offer lisings of classes, workshops, and private ...

Relieve the Tension in Your Life: Frank Kennedy - Alexander Technique Teacher in Ireland, providing consultation for group and individuals. Frank is well recognised and respected as an AT teacher and has practiced in Ireland for many years now.

Saint Louis Center for the Alexander Technique: Saint Louis Center for the Alexander Technique is a resource for information about the Alexander Technique

Sally Ahner - Alexander Teacher: Alexander Technique teacher in Nashville Tennesse - Sally Ahner works with others using Alexander Technique. The Alexander work is often in combination with music, singing, story, drama, art or dance, to help people discover who they really are. During group and/or individual lesson stud...

School for F.M. Alexander Studies: The School in Melbourne offers and accredited professional Alexander technique training plus a wide range of courses on the Alexander technique.

Sigal Bergman: Offering classes in New York City with a certified teacher. Includes applications and contact details.

Silver Fox Studio: Private lessons with Annette Schmidt in Walnut Creek, California. Features video introduction and FAQ.

Simply Wonderful: The Alexander Technique was developed last century by Tasmanian-born actor, Frederick Matthias Alexander Jill Freeman teaches the technique at workshops in north New Zealand and throughout Yorkshire in the United Kingdom She has been a qualified teacher since 1991

Studio Evolving: Studio Evolving is a unique and special place. Studio Evolving offers horse riding, yoga and accomodation in a healing environment. Alexander Technique in yoga, Alexander Technique in horse riding and life.

The Alexander Alliance: Teacher training and lessons in various locations.

The Alexander Learning Studio of Portland, Oregon: The Alexander Technique Learning Studio of Portland, Oregon. Explore how Alexander Technique lessons let you achieve effortless poise, posture, health and well-being, and learn about our studio.

The Alexander Studio: Lessons with Katherine-Scott Gillian, certified teacher. Charlottesville, Virginia.

The Alexander Technique: Alexander Technique with Constance Clare-Newman in Oakland and San Francisco Bay Area. Learn to correct excess tension by lessening effort in daily activities and specialized skills. Restore your natural coordination. Transform tension into attention. Increase ease and energy in mind and body.

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The Alexander Technique: Joshua Lyons offers individual lessons, workshops and group classes in Toronto, Canada.

The Alexander Technique: Alexander Technique teaches how to improve posture, balance, poise and flexibility by unlearning habits causing stiffness, tension and pain

The Alexander Technique: AmSAT Certified Lauri Blouke Kain offers lessons in Portland, Oregon.

The Alexander Technique Studios: The Alexander Technique: An intelligent way to relieve the pain and stress caused by everyday misuse of your body.

The Body Project: The Body Project - Alexander Technique lessons by certified instructor Elyse Shafarman in San Francisco, to reduce pain, prevent injury, and restore a forgotten sense of pleasure in the body.

The Sydney Alexander School: The Sydney Alexander School is located in Surry Hills, near the Sydney CBD. It provides individual sessions and professional training in the Alexander Technique.

The Texas Center for the Alexander Technique: The Alexander Technique is a movement education process which guides self-discovery and improvement in over-all use of your body. This TCAT site provides information useful for improving everyday body coordination, ease and comfort in movement, and specialized performance activities.

Tom Koch's Alexander Technique: Lessons and classes in Amsterdam, Holland.

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