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Herbs at a Glance Update: Black Cohosh
Mon, 01 Dec 2008 09:41:27 -0500
This fact sheet provides basic information about the black cohosh—common names, uses, potential side effects, and resources for more information. Black cohosh, a member of the buttercup family, is a plant native to North America. It was used in Native American medicine and was a home remedy in 19th-century America.What It Is Used ForBlack cohosh has a history of use for rheumatism (arthritis and muscle pain) but has been used more recently to treat hot flashes, night sweats, vaginal dryness, and other symptoms that can occur during menopause.Black cohosh has also been used for menstrual irregularities and premenstrual syndrome, and to induce labor.
December 1 Is World AIDS Day
Wed, 26 Nov 2008 14:20:34 -0500
AIDS (acquired immunodeficiency syndrome) is caused by the human immunodeficiency virus, or HIV. By killing or damaging cells of the body's immune system, HIV progressively destroys the body's ability to fight infections and certain cancers. These infections are caused by viruses or bacteria that usually do not make healthy people sick.Many people infected with HIV or living with AIDS may be considering the use of complementary and alternative medicine (CAM) to boost their immune system; treat complications of disease; or cope with side effects of conventional medications.
Ginkgo Evaluation of Memory (GEM) Study Fails To Show Benefit in Preventing Dementia in the Elderly
Tue, 18 Nov 2008 17:24:53 -0500
In a study published in the Journal of the American Medical Association, 240 milligrams per day of the dietary supplement Ginkgo biloba was found to be ineffective in reducing the development of dementia and Alzheimer's disease in older people. Researchers led by Steven T. DeKosky, M.D., conducted the trial known as the Ginkgo Evaluation of Memory (GEM) study at four clinical sites over the course of 8 years. GEM is the largest clinical trial ever to evaluate ginkgo's effect on the occurrence of dementia.Press Release—summary of results of the studyQuestions and Answers—detailed background information on the study
Evidence-based Complementary and Alternative Medicine - current issue
eCAM: An Emerging Linkage with Ethnopharmacology?
Cooper, E. L. Fri, 21 Nov 2008 00:00:00 -0000
Second World Ayurveda Congress (Theme: Ayurveda for the Future)--Inaugural Address: Part III
Mashelkar, R. A. Fri, 21 Nov 2008 00:00:00 -0000
A Review of CAM for Procedural Pain in Infancy: Part I. Sucrose and Non-nutritive Sucking
Tsao, J. C. I., Evans, S., Meldrum, M., Altman, T., Zeltzer, L. K. Fri, 21 Nov 2008 00:00:00 -0000
There is increasing concern regarding the number of painful medical procedures that infants must undergo and the potential risks of alleviating infant pain with conventional pharmacologic agents. This article is Part I of a two-part series that aims to provide an overview of the literature on complementary and alternative (CAM) approaches for pain and distress related to medical procedures among infants up to six weeks of age. The focus of this article is a review of the empirical literature on sucrose with or without non-nutritive sucking (NNS) for procedural pain in infancy. Computerized databases were searched for relevant studies including prior reviews and primary trials. The most robust evidence was found for the analgesic effects of sucrose with or without NNS on minor procedural pain in healthy full-term infants. Despite some methodological weaknesses, the literature to date supports the use of sucrose, NNS and other sweetened solutions for the management of procedural pain in infancy.
BMC Complementary and Alternative Medicine - Latest articles
Petiveria alliacea extracts uses multiple mechanisms to inhibit growth of human and mouse tumoral cells
Claudia P Uruena, Claudia Cifuentes, Diana M Castaneda, Amparo D Arango, Punit Kaur, Alexzander A Asea and Susana Fiorentino Tue, 18 Nov 2008 00:00:00 -0000
Background: There is ethnopharmacological evidence that Petiveria alliacea can have antitumor activity; however, the mechanism of its cytotoxic activity is not well understood. We assessed multiple in vitro biological activities of an ethyl acetate soluble plant fraction over several tumor cell lines. Methods: Tumor cell lines were evaluated using the following tests: trypan blue exclusion test, MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide], flow cytometry, cytoskeleton organization analysis, cell cycle, mitochondria membrane depolarization, clonogenicity test, DNA fragmentation test and differential protein expression by HPLC-Chip/MS analysis. F4 fraction characterization was made by HPLC-MS. Results: Petiveria alliacea fraction characterized by de-replication was found to alter actin cytoskeleton organization, induce G2 cell cycle arrest and cause apoptotic cell death in a mitochondria independent way. In addition, we found down regulation of cytoskeleton, chaperone, signal transduction proteins, and proteins involved in metabolic pathways. Finally up regulation of proteins involved in translation and intracellular degradation was also observed. Conclusions: The results of this study indicate that Petiveria alliacea exerts multiple biological activities in vitro consistent with cytotoxicity. Further studies in animal models are needed but Petiveria alliacea appears to be a good candidate to be used as an antitumor agent.
Induction of apoptosis of human primary osteoclasts treated with extracts from the medicinal plant Emblica officinalis
Letizia Penolazzi, Ilaria Lampronti, Monica Borgatti, Mahmud Tareq Hassan Khan, Margherita Zennaro, Roberta Piva and Roberto Gambari Thu, 30 Oct 2008 00:00:00 -0000
Background: Osteoclasts (OCs) are involved in rheumatoid arthritis and in several pathologies associated with bone loss. Recent results support the concept that some medicinal plants and derived natural products are of great interest for developing therapeutic strategies against bone disorders, including rheumatoid arthritis and osteoporosis. In this study we determined whether extracts of Emblica officinalis fruits display activity of possible interest for the treatment of rheumatoid arthritis and osteoporosis by activating programmed cell death of human primary osteoclasts. Methods: The effects of extracts from Emblica officinalis on differentiation and survival of human primary OCs cultures obtained from peripheral blood were determined by tartrate-acid resistant acid phosphatase (TRAP)-positivity and colorimetric MTT assay. The effects of Emblica officinalis extracts on induction of OCs apoptosis were studied using TUNEL and immunocytochemical analysis of FAS receptor expression. Finally, in vitro effects of Emblica officinalis extracts on NF-kB transcription factor activity were determined by gel shift experiments. Results: Extracts of Emblica officinalis were able to induce programmed cell death of mature OCs, without altering, at the concentrations employed in our study, the process of osteoclastogenesis. Emblica officinalis increased the expression levels of Fas, a critical member of the apoptotic pathway. Gel shift experiments demonstrated that Emblica officinalis extracts act by interfering with NF-kB activity, a transcription factor involved in osteoclast biology. The data obtained demonstrate that Emblica officinalis extracts selectively compete with the binding of transcription factor NF-kB to its specific target DNA sequences. This effect might explain the observed effects of Emblica officinalis on the expression levels of interleukin-6, a NF-kB specific target gene. Conclusion: Induction of apoptosis of osteoclasts could be an important strategy both in interfering with rheumatoid arthritis complications of the bone skeleton leading to joint destruction, and preventing and reducing osteoporosis. Accordingly, we suggest the application of Emblica officinalis extracts as an alternative tool for therapy applied to bone diseases.
TCMGeneDIT: a database for associated traditional Chinese medicine, gene and disease information using text mining
Yu-Ching Fang, Hsuan-Cheng Huang, Hsin-Hsi Chen and Hsueh-Fen Juan Tue, 14 Oct 2008 00:00:00 -0000
Background: Traditional Chinese Medicine (TCM), a complementary and alternative medical system in Western countries, has been used to treat various diseases over thousands of years in East Asian countries. In recent years, many herbal medicines were found to exhibit a variety of effects through regulating a wide range of gene expressions or protein activities. As available TCM data continue to accumulate rapidly, an urgent need for exploring these resources systematically is imperative, so as to effectively utilize the large volume of literature. Methods: TCM, gene, disease, biological pathway and protein-protein interaction information were collected from public databases. For association discovery, the TCM names, gene names, disease names, TCM ingredients and effects were used to annotate the literature corpus obtained from PubMed. The concept to mine entity associations was based on hypothesis testing and collocation analysis. The annotated corpus was processed with natural language processing tools and rule-based approaches were applied to the sentences for extracting the relations between TCM effecters and effects. Results: We developed a database, TCMGeneDIT, to provide association information about TCMs, genes, diseases, TCM effects and TCM ingredients mined from vast amount of biomedical literature. Integrated protein-protein interaction and biological pathways information are also available for exploring the regulations of genes associated with TCM curative effects. In addition, the transitive relationships among genes, TCMs and diseases could be inferred through the shared intermediates. Furthermore, TCMGeneDIT is useful in understanding the possible therapeutic mechanisms of TCMs via gene regulations and deducing synergistic or antagonistic contributions of the prescription components to the overall therapeutic effects. The database is now available at http://tcm.lifescience.ntu.edu.tw/. Conclusion: TCMGeneDIT is a unique database that offers diverse association information on TCMs. This database integrates TCMs with biomedical studies that would facilitate clinical research and elucidate the possible therapeutic mechanisms of TCMs and gene regulations.
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Herbs at a Glance Update: Black Cohosh
Mon, 01 Dec 2008 09:41:27 -0500
This fact sheet provides basic information about the black cohosh—common names, uses, potential side effects, and resources for more information. Black cohosh, a member of the buttercup family, is a plant native to North America. It was used in Native American medicine and was a home remedy in 19th-century America.What It Is Used ForBlack cohosh has a history of use for rheumatism (arthritis and muscle pain) but has been used more recently to treat hot flashes, night sweats, vaginal dryness, and other symptoms that can occur during menopause.Black cohosh has also been used for menstrual irregularities and premenstrual syndrome, and to induce labor.
December 1 Is World AIDS Day
Wed, 26 Nov 2008 14:20:34 -0500
AIDS (acquired immunodeficiency syndrome) is caused by the human immunodeficiency virus, or HIV. By killing or damaging cells of the body's immune system, HIV progressively destroys the body's ability to fight infections and certain cancers. These infections are caused by viruses or bacteria that usually do not make healthy people sick.Many people infected with HIV or living with AIDS may be considering the use of complementary and alternative medicine (CAM) to boost their immune system; treat complications of disease; or cope with side effects of conventional medications.
Ginkgo Evaluation of Memory (GEM) Study Fails To Show Benefit in Preventing Dementia in the Elderly
Tue, 18 Nov 2008 17:24:53 -0500
In a study published in the Journal of the American Medical Association, 240 milligrams per day of the dietary supplement Ginkgo biloba was found to be ineffective in reducing the development of dementia and Alzheimer's disease in older people. Researchers led by Steven T. DeKosky, M.D., conducted the trial known as the Ginkgo Evaluation of Memory (GEM) study at four clinical sites over the course of 8 years. GEM is the largest clinical trial ever to evaluate ginkgo's effect on the occurrence of dementia.Press Release—summary of results of the studyQuestions and Answers—detailed background information on the study
Evidence-based Complementary and Alternative Medicine - current issue
eCAM: An Emerging Linkage with Ethnopharmacology?
Cooper, E. L. Fri, 21 Nov 2008 00:00:00 -0000
Second World Ayurveda Congress (Theme: Ayurveda for the Future)--Inaugural Address: Part III
Mashelkar, R. A. Fri, 21 Nov 2008 00:00:00 -0000
A Review of CAM for Procedural Pain in Infancy: Part I. Sucrose and Non-nutritive Sucking
Tsao, J. C. I., Evans, S., Meldrum, M., Altman, T., Zeltzer, L. K. Fri, 21 Nov 2008 00:00:00 -0000
There is increasing concern regarding the number of painful medical procedures that infants must undergo and the potential risks of alleviating infant pain with conventional pharmacologic agents. This article is Part I of a two-part series that aims to provide an overview of the literature on complementary and alternative (CAM) approaches for pain and distress related to medical procedures among infants up to six weeks of age. The focus of this article is a review of the empirical literature on sucrose with or without non-nutritive sucking (NNS) for procedural pain in infancy. Computerized databases were searched for relevant studies including prior reviews and primary trials. The most robust evidence was found for the analgesic effects of sucrose with or without NNS on minor procedural pain in healthy full-term infants. Despite some methodological weaknesses, the literature to date supports the use of sucrose, NNS and other sweetened solutions for the management of procedural pain in infancy.
BMC Complementary and Alternative Medicine - Latest articles
Petiveria alliacea extracts uses multiple mechanisms to inhibit growth of human and mouse tumoral cells
Claudia P Uruena, Claudia Cifuentes, Diana M Castaneda, Amparo D Arango, Punit Kaur, Alexzander A Asea and Susana Fiorentino Tue, 18 Nov 2008 00:00:00 -0000
Background: There is ethnopharmacological evidence that Petiveria alliacea can have antitumor activity; however, the mechanism of its cytotoxic activity is not well understood. We assessed multiple in vitro biological activities of an ethyl acetate soluble plant fraction over several tumor cell lines. Methods: Tumor cell lines were evaluated using the following tests: trypan blue exclusion test, MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide], flow cytometry, cytoskeleton organization analysis, cell cycle, mitochondria membrane depolarization, clonogenicity test, DNA fragmentation test and differential protein expression by HPLC-Chip/MS analysis. F4 fraction characterization was made by HPLC-MS. Results: Petiveria alliacea fraction characterized by de-replication was found to alter actin cytoskeleton organization, induce G2 cell cycle arrest and cause apoptotic cell death in a mitochondria independent way. In addition, we found down regulation of cytoskeleton, chaperone, signal transduction proteins, and proteins involved in metabolic pathways. Finally up regulation of proteins involved in translation and intracellular degradation was also observed. Conclusions: The results of this study indicate that Petiveria alliacea exerts multiple biological activities in vitro consistent with cytotoxicity. Further studies in animal models are needed but Petiveria alliacea appears to be a good candidate to be used as an antitumor agent.
Induction of apoptosis of human primary osteoclasts treated with extracts from the medicinal plant Emblica officinalis
Letizia Penolazzi, Ilaria Lampronti, Monica Borgatti, Mahmud Tareq Hassan Khan, Margherita Zennaro, Roberta Piva and Roberto Gambari Thu, 30 Oct 2008 00:00:00 -0000
Background: Osteoclasts (OCs) are involved in rheumatoid arthritis and in several pathologies associated with bone loss. Recent results support the concept that some medicinal plants and derived natural products are of great interest for developing therapeutic strategies against bone disorders, including rheumatoid arthritis and osteoporosis. In this study we determined whether extracts of Emblica officinalis fruits display activity of possible interest for the treatment of rheumatoid arthritis and osteoporosis by activating programmed cell death of human primary osteoclasts. Methods: The effects of extracts from Emblica officinalis on differentiation and survival of human primary OCs cultures obtained from peripheral blood were determined by tartrate-acid resistant acid phosphatase (TRAP)-positivity and colorimetric MTT assay. The effects of Emblica officinalis extracts on induction of OCs apoptosis were studied using TUNEL and immunocytochemical analysis of FAS receptor expression. Finally, in vitro effects of Emblica officinalis extracts on NF-kB transcription factor activity were determined by gel shift experiments. Results: Extracts of Emblica officinalis were able to induce programmed cell death of mature OCs, without altering, at the concentrations employed in our study, the process of osteoclastogenesis. Emblica officinalis increased the expression levels of Fas, a critical member of the apoptotic pathway. Gel shift experiments demonstrated that Emblica officinalis extracts act by interfering with NF-kB activity, a transcription factor involved in osteoclast biology. The data obtained demonstrate that Emblica officinalis extracts selectively compete with the binding of transcription factor NF-kB to its specific target DNA sequences. This effect might explain the observed effects of Emblica officinalis on the expression levels of interleukin-6, a NF-kB specific target gene. Conclusion: Induction of apoptosis of osteoclasts could be an important strategy both in interfering with rheumatoid arthritis complications of the bone skeleton leading to joint destruction, and preventing and reducing osteoporosis. Accordingly, we suggest the application of Emblica officinalis extracts as an alternative tool for therapy applied to bone diseases.
TCMGeneDIT: a database for associated traditional Chinese medicine, gene and disease information using text mining
Yu-Ching Fang, Hsuan-Cheng Huang, Hsin-Hsi Chen and Hsueh-Fen Juan Tue, 14 Oct 2008 00:00:00 -0000
Background: Traditional Chinese Medicine (TCM), a complementary and alternative medical system in Western countries, has been used to treat various diseases over thousands of years in East Asian countries. In recent years, many herbal medicines were found to exhibit a variety of effects through regulating a wide range of gene expressions or protein activities. As available TCM data continue to accumulate rapidly, an urgent need for exploring these resources systematically is imperative, so as to effectively utilize the large volume of literature. Methods: TCM, gene, disease, biological pathway and protein-protein interaction information were collected from public databases. For association discovery, the TCM names, gene names, disease names, TCM ingredients and effects were used to annotate the literature corpus obtained from PubMed. The concept to mine entity associations was based on hypothesis testing and collocation analysis. The annotated corpus was processed with natural language processing tools and rule-based approaches were applied to the sentences for extracting the relations between TCM effecters and effects. Results: We developed a database, TCMGeneDIT, to provide association information about TCMs, genes, diseases, TCM effects and TCM ingredients mined from vast amount of biomedical literature. Integrated protein-protein interaction and biological pathways information are also available for exploring the regulations of genes associated with TCM curative effects. In addition, the transitive relationships among genes, TCMs and diseases could be inferred through the shared intermediates. Furthermore, TCMGeneDIT is useful in understanding the possible therapeutic mechanisms of TCMs via gene regulations and deducing synergistic or antagonistic contributions of the prescription components to the overall therapeutic effects. The database is now available at http://tcm.lifescience.ntu.edu.tw/. Conclusion: TCMGeneDIT is a unique database that offers diverse association information on TCMs. This database integrates TCMs with biomedical studies that would facilitate clinical research and elucidate the possible therapeutic mechanisms of TCMs and gene regulations.

Sites:
Oriental Medicine National Coalition: AOMNC was formed to support the passage of Federal Acupuncture Bill and to advocate for the elimination of discriminatory reimbursement practices.Accreditation Commission for Acupuncture and Oriental Medicine: The Accreditation Commission for Acupuncture and Oriental Medicine (ACAOM) (formerly the National Accreditation Commission for Schools and Colleges of Acupuncture and Oriental Medicine - NACSCAOM) was established in June 1982 by the Council of Colleges of Acupuncture and Ori, The Accreditation Co...
Acupuncture and Oriental Medicine Alliance: AOMAlliance is an umbrella organization comprised of practitioners, teachers, schools, venders and users of energetic medicine. Established in 1994, Olalla, WA.
American Academy of Medical Acupuncture: AAMA is a physician organization promoting the integration of acupuncture with Western medical training and a comprehensive approach to health care.
American Association of Oriental Medicine: AAOM is a professional membership organization of licensed Oriental medicine practitioners who are committed to high ethical, educational, and regulatory standards, to ensure the competent provision of Oriental medicine to the public. Since 1981. Maryland.
American Chinese Medicine Association (ACMA): ACMA Treatment Center is a premier Chinese Medicine treatment center in the United States. Many diseases (including cancers) treatment results at the ACMA Treatment Center are in the leading positions in the United States based on both Western Medicine and Chinese Medicine criteria. List of dis...
Australian Acupuncture and Chinese Medicine Association, Ltd.: AACMA is a national professional association of acupuncture and traditional Chinese medicine practitioners. West End, Queensland, Australia.
British Acupuncture Council: The British Acupuncture Council is the UK's main regulatory body for the practice of traditional acupuncture by over 2800 acupuncturists. Locate a BAcC practitioner near you.
British Medical Acupuncture Society: The British Medical Acupuncture Society
California State Oriental Medical Association: California State Oriental Medical Association
Canadian Academy of Chinese Traditional Health Sciences: The Canadian Society of Chinese Medicine and Acupuncture, www.tcmcanada.org, Web designed by Oliver YANG, E IMAGE INC. www.eimage.ca
Chinese Medicine and Acupuncture Association of Canada: Welcome to the Chinese Medicine and Acupuncture Association of Canada. This site should be viewed at 800x600 screen resolution.
Council of Acupuncture and Oriental Medicine Associations: Advocates for access to excellence in acupuncture, oriental medicine, and integr
European Federation for Oriental Medicine: Wil je meer weten over acupunctuur of zoek je een acupuncturist in je buurt, bezoek dan de Eufom site...
Florida Association of Oriental Medicine: FAOM is a professional association serving its membership to promote and protect the interests of Florida acupuncture physicians and the practice of Oriental Medicine.
Florida State Oriental Medical Association: Get information on any traditional Oriental medicine practitioners in the state of Florida. Oriental practitioners, FSOMA members and the public are welcome.
International Council of Medical Acupuncture and Related Techniques: ICMART stands for International Council of Medical Acupuncture and Related Techniques
Maine Association of Acupuncture and Oriental Medicine (MAAOM): site description here
Michigan Association of Acupuncture and Oriental Medicine: MAAOM provides a directory of practitioners and educational information on acupuncture and Oriental medicine.
Michigan Medical Acupuncture Association: Michigan Medical Acupuncture Association provides educational and authoritative information on acupuncture and oriental medicine.
Modernized Chinese Medicine International Association: MCMIA promotes the modernization and globalization of Chinese medicine. Multilingual site. Hong Kong.
National Certification Commission for Acupuncture and Oriental Medicine: NCCAOM is a private non-profit organization which develops, promotes, and administers examinations and certifications for acupuncture, chinese herbology, and asian bodywork. Established 1982. Alexandria, VA.
National Oriental Medicine Accreditation Agency: National Oriental Medicine Accreditation Agency
New Hampshire Association for Acupuncture and Oriental Medicine: NHAAOM is a licensed acupuncturist organization expanding public awareness, promoting access, and improving integration of Oriental Medicine into the American health care system.
North Carolina Association of Acupuncture and Oriental Medicine: NCAAOM is a licensed acupuncturist organization promoting and fostering qualifications, regulations, education, practice, and research in Oriental Medicine since 1987.
Oregon Acupuncture Association: OAA is a licensed acupuncturirst organization which posts newsletters, reports, and other useful information on its website.
Oriental Medicine Association of New Mexico: Acupuncture New Mexico - Oriental Medicine Association of New Mexico website, a database of Doctors of Oriental Medicine throughout New Mexico.
Society for Acupuncture Research: SAR is a charitable research organization promoting scientific inquiries into clinical efficacy, physiological mechanisms, patterns of use, and theoretical foundations. Washington, DC.
The Acupuncture Society: TAS is a professional body of acupuncture practitioners promoting the development of Chinese acupuncture, herbal medicine and diagnosis as an effective medical practice. United Kingdom.
